Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Illinois-Chicago (139) | 65 | 61 | Northern Illinois (326) | Final | L | -4 |
| 2 | 2020-12-02 | SIU-Edwardsville (248) | 73 | 53 | Northern Illinois (326) | Final | L | -20 |
| 3 | 2020-12-05 | Northern Illinois (326) | 59 | 89 | Pittsburgh (108) | Final | L | -30 |
| 4 | 2020-12-08 | Ball State (298) | 79 | 70 | Northern Illinois (326) | Final/OT | L | -9 |
| 5 | 2020-12-13 | Northern Illinois (326) | 53 | 106 | Iowa (28) | Final | L | -53 |
| 6 | 2020-12-15 | SIU-Edwardsville (248) | 0 | 0 | Northern Illinois (326) | Cancelled | - | - |
| 7 | 2020-12-18 | Chicago State (351) | 54 | 64 | Northern Illinois (326) | Final | W | 10 |
| 8 | 2020-12-22 | Northern Illinois (326) | 55 | 78 | Toledo (135) | Final | L | -23 |
| 9 | 2021-01-02 | Bowling Green (168) | 68 | 42 | Northern Illinois (326) | Final | L | -26 |
| 10 | 2021-01-05 | Northern Illinois (326) | 73 | 76 | Ohio (218) | Final | L | -3 |
| 11 | 2021-01-09 | Northern Illinois (326) | 58 | 70 | Miami (OH) (40) | Final | L | -12 |
| 12 | 2021-01-12 | Akron (59) | 65 | 67 | Northern Illinois (326) | Final | W | 2 |
| 13 | 2021-01-16 | Northern Illinois (326) | 58 | 78 | Ball State (298) | Final | L | -20 |
| 14 | 2021-01-19 | Ohio (218) | 0 | 0 | Northern Illinois (326) | Cancelled | - | - |
| 15 | 2021-01-23 | Buffalo (219) | 0 | 0 | Northern Illinois (326) | Postponed | - | - |
| 16 | 2021-01-26 | Northern Illinois (326) | 0 | 0 | Bowling Green (168) | Cancelled | - | - |
| 17 | 2021-01-29 | Eastern Michigan (277) | 0 | 0 | Northern Illinois (326) | Cancelled | - | - |
| 18 | 2021-01-30 | Eastern Michigan (297) | 0 | 0 | Northern Illinois (324) | Cancelled | - | - |
| 19 | 2021-02-02 | Northern Illinois (326) | 0 | 0 | Western Michigan (304) | Cancelled | - | - |
| 20 | 2021-02-06 | Central Michigan (269) | 0 | 0 | Northern Illinois (328) | Cancelled | - | - |
| 21 | 2021-02-09 | Toledo (135) | 0 | 0 | Northern Illinois (326) | Cancelled | - | - |
| 22 | 2021-02-13 | Northern Illinois (326) | 58 | 80 | Kent State (107) | Final | L | -22 |
| 23 | 2021-02-16 | Northern Illinois (326) | 76 | 81 | Akron (59) | Final | L | -5 |
| 24 | 2021-02-20 | Miami (OH) (40) | 69 | 64 | Northern Illinois (326) | Final | L | -5 |
| 25 | 2021-02-23 | Buffalo (219) | 102 | 74 | Northern Illinois (326) | Final | L | -28 |
| 26 | 2021-02-27 | Northern Illinois (326) | 57 | 91 | Eastern Michigan (277) | Final | L | -34 |
| 27 | 2021-03-02 | Western Michigan (304) | 73 | 63 | Northern Illinois (326) | Final | L | -10 |
| 28 | 2021-03-05 | Northern Illinois (326) | 79 | 74 | Central Michigan (311) | Final | W | 5 |