Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Eastern Michigan (277) | 67 | 83 | Michigan State (10) | Final | L | -16 |
| 2 | 2020-11-28 | Eastern Michigan (195) | SIU-Edwardsville (337) | Cancelled | - | - | ||
| 3 | 2020-12-04 | Toledo (135) | 91 | 74 | Eastern Michigan (277) | Final | L | -17 |
| 4 | 2020-12-09 | Adrian | 35 | 95 | Eastern Michigan (277) | Final | W | 60 |
| 5 | 2020-12-16 | Eastern Michigan (277) | 0 | 0 | Valparaiso (156) | Cancelled | - | - |
| 6 | 2020-12-16 | Eastern Michigan (251) | Valparaiso (288) | Cancelled | - | - | ||
| 7 | 2020-12-27 | Olivet | 65 | 94 | Eastern Michigan (277) | Final | W | 29 |
| 8 | 2020-12-29 | Central Michigan (311) | 87 | 60 | Eastern Michigan (277) | Final | L | -27 |
| 9 | 2021-01-02 | Kent State (107) | 0 | 0 | Eastern Michigan (277) | Cancelled | - | - |
| 10 | 2021-01-05 | Eastern Michigan (286) | 0 | 0 | Buffalo (185) | Cancelled | - | - |
| 11 | 2021-01-05 | Akron (59) | 0 | 0 | Eastern Michigan (277) | Postponed | - | - |
| 12 | 2021-01-09 | Akron (59) | 59 | 71 | Eastern Michigan (277) | Final | W | 12 |
| 13 | 2021-01-12 | Eastern Michigan (277) | 63 | 96 | Toledo (135) | Final | L | -33 |
| 14 | 2021-01-14 | Calvin | 56 | 67 | Eastern Michigan (277) | Final | W | 11 |
| 15 | 2021-01-16 | Eastern Michigan (277) | 64 | 75 | Central Michigan (311) | Final | L | -11 |
| 16 | 2021-01-19 | Western Michigan (304) | 0 | 0 | Eastern Michigan (277) | Cancelled | - | - |
| 17 | 2021-01-21 | Eastern Michigan (277) | 77 | 92 | Buffalo (219) | Final | L | -15 |
| 18 | 2021-01-23 | Miami (OH) (40) | 85 | 63 | Eastern Michigan (277) | Final | L | -22 |
| 19 | 2021-01-26 | Eastern Michigan (277) | 65 | 86 | Akron (59) | Final | L | -21 |
| 20 | 2021-01-29 | Eastern Michigan (277) | 0 | 0 | Northern Illinois (326) | Cancelled | - | - |
| 21 | 2021-01-30 | Eastern Michigan (297) | 0 | 0 | Northern Illinois (324) | Cancelled | - | - |
| 22 | 2021-02-02 | Bowling Green (168) | 0 | 0 | Eastern Michigan (277) | Postponed | - | - |
| 23 | 2021-02-06 | Eastern Michigan (277) | 0 | 0 | Ohio (218) | Postponed | - | - |
| 24 | 2021-02-09 | Eastern Michigan (277) | 0 | 0 | Miami (OH) (40) | Cancelled | - | - |
| 25 | 2021-02-13 | Eastern Michigan (277) | 0 | 0 | Ball State (298) | Postponed | - | - |
| 26 | 2021-02-16 | Buffalo (219) | 0 | 0 | Eastern Michigan (277) | Cancelled | - | - |
| 27 | 2021-02-20 | Eastern Michigan (277) | 51 | 64 | Kent State (107) | Final | L | -13 |
| 28 | 2021-02-23 | Bowling Green (168) | 82 | 69 | Eastern Michigan (277) | Final | L | -13 |
| 29 | 2021-02-25 | Eastern Michigan (277) | 67 | 86 | Ohio (218) | Final | L | -19 |
| 30 | 2021-02-27 | Northern Illinois (326) | 57 | 91 | Eastern Michigan (277) | Final | W | 34 |
| 31 | 2021-03-02 | Eastern Michigan (277) | 65 | 100 | Ball State (298) | Final | L | -35 |
| 32 | 2021-03-05 | Eastern Michigan (277) | 64 | 63 | Western Michigan (304) | Final | W | 1 |