Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-15 | Milligan | 58 | 80 | Marshall (107) | Final | L | -22 |
| 2 | 2021-11-27 | Milligan | 49 | 88 | Mercer (309) | Final | L | -39 |
| 3 | 2021-12-05 | Milligan | 55 | 98 | Austin Peay (224) | Final | L | -43 |
| 4 | 2021-12-21 | Milligan | 54 | 114 | UNC-Asheville (244) | Final | L | -60 |