Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2024-11-04 | Texas Southern (317) | 69 | 78 | Xavier (92) | Final | W | 9 |
| 2 | 2024-11-08 | IU-Indy (221) | 80 | 94 | Xavier (25) | Final | W | 14 |
| 3 | 2024-11-12 | Jackson State (356) | 57 | 94 | Xavier (50) | Final | W | 37 |
| 4 | 2024-11-16 | Wake Forest (81) | 60 | 75 | Xavier (23) | Final | W | 15 |
| 5 | 2024-11-20 | Siena (160) | 55 | 80 | Xavier (92) | Final | W | 25 |
| 6 | 2024-11-25 | Xavier (16) | 75 | 66 | South Carolina (110) | Final | W | 9 |
| 7 | 2024-11-27 | Xavier (54) | 53 | 78 | Michigan (19) | Final | L | -25 |
| 8 | 2024-12-01 | South Carolina State (274) | 68 | 71 | Xavier (55) | Final | W | 3 |
| 9 | 2024-12-05 | Xavier (72) | 72 | 76 | TCU (93) | Final | L | -4 |
| 10 | 2024-12-10 | Morgan State (353) | 58 | 119 | Xavier (63) | Final | W | 61 |
| 11 | 2024-12-14 | Xavier (78) | 65 | 68 | Cincinnati (52) | Final | L | -3 |
| 12 | 2024-12-18 | Xavier (80) | 89 | 94 | Connecticut (28) | Final (OT) | L | -5 |
| 13 | 2024-12-21 | Marquette (8) | 72 | 70 | Xavier (84) | Final | L | -2 |
| 14 | 2024-12-31 | Seton Hall (194) | 72 | 94 | Xavier (74) | Final | W | 22 |
| 15 | 2025-01-03 | Xavier (75) | 63 | 69 | Georgetown (59) | Final | L | -6 |
| 16 | 2025-01-07 | St. John's (30) | 82 | 72 | Xavier (79) | Final | L | -10 |
| 17 | 2025-01-11 | Xavier (76) | 77 | 63 | DePaul (124) | Final | W | 14 |
| 18 | 2025-01-14 | Villanova (80) | 63 | 69 | Xavier (67) | Final | W | 6 |
| 19 | 2025-01-18 | Xavier (59) | 59 | 57 | Marquette (15) | Final | W | 2 |
| 20 | 2025-01-22 | Xavier (64) | 71 | 79 | St. John's (23) | Final (OT) | L | -8 |
| 21 | 2025-01-25 | Connecticut (46) | 72 | 76 | Xavier (60) | Final | W | 4 |
| 22 | 2025-01-29 | Xavier (61) | 77 | 86 | Creighton (35) | Final | L | -9 |
| 23 | 2025-02-04 | Georgetown (83) | 69 | 74 | Xavier (56) | Final | W | 5 |
| 24 | 2025-02-09 | Xavier (92) | 68 | 80 | Villanova (29) | Final | L | -12 |
| 25 | 2025-02-12 | Xavier (60) | 91 | 82 | Providence (106) | Final | W | 9 |
| 26 | 2025-02-15 | DePaul (149) | 68 | 85 | Xavier (57) | Final | W | 17 |
| 27 | 2025-02-18 | Butler (90) | 63 | 76 | Xavier (54) | Final | W | 13 |
| 28 | 2025-02-23 | Xavier (54) | 73 | 66 | Seton Hall (216) | Final | W | 7 |
| 29 | 2025-03-01 | Creighton (78) | 61 | 83 | Xavier (92) | Final | W | 22 |
| 30 | 2025-03-05 | Xavier (51) | 91 | 78 | Butler (94) | Final | W | 13 |
| 31 | 2025-03-08 | Providence (118) | 68 | 76 | Xavier (49) | Final | W | 8 |
| 32 | 2025-03-13 | Marquette (32) | 89 | 87 | Xavier (50) | Final | L | -2 |
| 33 | 2025-03-19 | Xavier (51) | 86 | 80 | Texas (45) | Final | W | 6 |
| 34 | 2025-03-21 | Xavier (51) | 73 | 86 | Illinois (24) | Final | L | -13 |