Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2024-11-04 | Brown (295) | 71 | 72 | Siena (160) | Final/OT | W | 1 |
| 2 | 2024-11-08 | Siena (44) | 90 | 88 | Bryant (232) | Final (OT) | W | 2 |
| 3 | 2024-11-12 | American (188) | 66 | 74 | Siena (56) | Final | W | 8 |
| 4 | 2024-11-16 | Siena (134) | 60 | 70 | Albany (149) | Final | L | -10 |
| 5 | 2024-11-20 | Siena (160) | 55 | 80 | Xavier (92) | Final | L | -25 |
| 6 | 2024-11-25 | Siena (199) | 58 | 70 | Miami (OH) (152) | Final | L | -12 |
| 7 | 2024-11-26 | Jacksonville (155) | 75 | 64 | Siena (215) | Final | L | -11 |
| 8 | 2024-11-30 | Siena (189) | 71 | 58 | Bucknell (194) | Final | W | 13 |
| 9 | 2024-12-06 | Siena (213) | 68 | 69 | Niagara (270) | Final | L | -1 |
| 10 | 2024-12-08 | Siena (210) | 66 | 53 | Canisius (362) | Final | W | 13 |
| 11 | 2024-12-17 | St. Bonaventure (47) | 65 | 48 | Siena (219) | Final | L | -17 |
| 12 | 2024-12-20 | Holy Cross (185) | 78 | 70 | Siena (243) | Final | L | -8 |
| 13 | 2024-12-30 | Siena (223) | 83 | 77 | Cornell (160) | Final | W | 6 |
| 14 | 2025-01-03 | Manhattan (242) | 95 | 103 | Siena (213) | Final (2OT) | W | 8 |
| 15 | 2025-01-05 | Iona (283) | 74 | 73 | Siena (223) | Final | L | -1 |
| 16 | 2025-01-10 | Siena (243) | 53 | 72 | Quinnipiac (212) | Final | L | -19 |
| 17 | 2025-01-16 | Sacred Heart (301) | 75 | 93 | Siena (230) | Final | W | 18 |
| 18 | 2025-01-18 | Siena (236) | 58 | 64 | Merrimack (198) | Final | L | -6 |
| 19 | 2025-01-23 | Mount St Mary's (224) | 68 | 82 | Siena (226) | Final | W | 14 |
| 20 | 2025-01-25 | Siena (234) | 68 | 72 | Iona (271) | Final | L | -4 |
| 21 | 2025-01-31 | Siena (239) | 67 | 72 | Marist (143) | Final | L | -5 |
| 22 | 2025-02-02 | Quinnipiac (193) | 75 | 84 | Siena (230) | Final | W | 9 |
| 23 | 2025-02-06 | Saint Peter's (299) | 63 | 77 | Siena (223) | Final | W | 14 |
| 24 | 2025-02-08 | Siena (229) | 59 | 61 | Rider (314) | Final | L | -2 |
| 25 | 2025-02-14 | Marist (166) | 65 | 64 | Siena (235) | Final | L | -1 |
| 26 | 2025-02-16 | Siena (234) | 80 | 73 | Sacred Heart (276) | Final | W | 7 |
| 27 | 2025-02-21 | Niagara (316) | 60 | 94 | Siena (225) | Final | W | 34 |
| 28 | 2025-02-23 | Canisius (356) | 93 | 88 | Siena (235) | Final | L | -5 |
| 29 | 2025-03-02 | Siena (241) | 79 | 85 | Mount St Mary's (216) | Final | L | -6 |
| 30 | 2025-03-06 | Fairfield (316) | 64 | 68 | Siena (240) | Final | W | 4 |
| 31 | 2025-03-08 | Siena (245) | 66 | 78 | Manhattan (223) | Final | L | -12 |
| 32 | 2025-03-11 | Siena (252) | 76 | 78 | Rider (289) | Final | L | -2 |