Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2024-11-04 | Saint Louis (31) | 78 | 85 | Santa Clara (42) | Final | L | -7 |
| 2 | 2024-11-10 | Avila | 44 | 95 | Saint Louis (251) | Final | W | 51 |
| 3 | 2024-11-16 | Loyola Marymount (298) | 71 | 77 | Saint Louis (215) | Final | W | 6 |
| 4 | 2024-11-22 | Wichita State (38) | 88 | 63 | Saint Louis (230) | Final | L | -25 |
| 5 | 2024-11-25 | Quinnipiac (268) | 67 | 81 | Saint Louis (193) | Final | W | 14 |
| 6 | 2024-11-27 | UMass-Lowell (167) | 90 | 93 | Saint Louis (139) | Final | W | 3 |
| 7 | 2024-12-02 | Jackson State (349) | 66 | 74 | Saint Louis (137) | Final | W | 8 |
| 8 | 2024-12-05 | Saint Louis (151) | 61 | 78 | San Francisco (44) | Final | L | -17 |
| 9 | 2024-12-08 | Chicago State (360) | 62 | 85 | Saint Louis (128) | Final | W | 23 |
| 10 | 2024-12-15 | Saint Louis (151) | 77 | 81 | Illinois State (149) | Final | L | -4 |
| 11 | 2024-12-18 | Wofford (212) | 74 | 71 | Saint Louis (172) | Final | L | -3 |
| 12 | 2024-12-22 | Saint Louis (175) | 72 | 73 | Grand Canyon (100) | Final | L | -1 |
| 13 | 2024-12-28 | William Woods | 57 | 78 | Saint Louis (182) | Final | W | 21 |
| 14 | 2024-12-31 | Saint Louis (158) | 88 | 63 | Fordham (177) | Final | W | 25 |
| 15 | 2025-01-03 | Saint Joseph's (101) | 57 | 73 | Saint Louis (134) | Final | W | 16 |
| 16 | 2025-01-08 | St. Bonaventure (58) | 68 | 73 | Saint Louis (121) | Final | W | 5 |
| 17 | 2025-01-14 | Saint Louis (133) | 62 | 78 | Virginia Commonwealth (71) | Final | L | -16 |
| 18 | 2025-01-18 | Saint Louis (126) | 63 | 59 | Richmond (253) | Final | W | 4 |
| 19 | 2025-01-22 | La Salle (160) | 52 | 64 | Saint Louis (117) | Final | W | 12 |
| 20 | 2025-01-25 | Saint Louis (125) | 61 | 67 | George Washington (123) | Final | L | -6 |
| 21 | 2025-01-28 | Virginia Commonwealth (64) | 69 | 78 | Saint Louis (111) | Final | W | 9 |
| 22 | 2025-01-31 | Dayton (73) | 71 | 63 | Saint Louis (116) | Final | L | -8 |
| 23 | 2025-02-04 | Saint Louis (112) | 73 | 71 | Massachusetts (192) | Final | W | 2 |
| 24 | 2025-02-07 | Saint Louis (120) | 63 | 76 | Saint Joseph's (90) | Final | L | -13 |
| 25 | 2025-02-11 | George Mason (56) | 76 | 74 | Saint Louis (121) | Final (OT) | L | -2 |
| 26 | 2025-02-14 | Saint Louis (133) | 69 | 78 | Loyola-Chicago (110) | Final | L | -9 |
| 27 | 2025-02-22 | Rhode Island (106) | 66 | 81 | Saint Louis (121) | Final | W | 15 |
| 28 | 2025-02-25 | Saint Louis (31) | 57 | 56 | Davidson (111) | Final | W | 1 |
| 29 | 2025-03-01 | Loyola-Chicago (263) | 67 | 98 | Saint Louis (31) | Final | W | 31 |
| 30 | 2025-03-04 | Saint Louis (114) | 67 | 75 | Dayton (68) | Final | L | -8 |
| 31 | 2025-03-08 | Duquesne (164) | 88 | 90 | Saint Louis (111) | Final (OT) | W | 2 |
| 32 | 2025-03-13 | Davidson (146) | 75 | 83 | Saint Louis (111) | Final | W | 8 |
| 33 | 2025-03-14 | Saint Louis (111) | 64 | 72 | Loyola-Chicago (92) | Final | L | -8 |
| 34 | 2025-03-18 | Saint Louis (117) | 78 | 103 | Arkansas State (92) | Final | L | -25 |