Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Radford (188) | 69 | 79 | Marquette (14) | Final | W | 10 |
| 2 | 2022-11-10 | Central Michigan (312) | 73 | 97 | Marquette (14) | Final | W | 24 |
| 3 | 2022-11-15 | Marquette (14) | 70 | 75 | Purdue (4) | Final | L | -5 |
| 4 | 2022-11-17 | Long Island (363) | 58 | 95 | Marquette (14) | Final | W | 37 |
| 5 | 2022-11-21 | Marquette (14) | 55 | 58 | Mississippi State (45) | Final | L | -3 |
| 6 | 2022-11-23 | Marquette (14) | 84 | 60 | Georgia Tech (168) | Final | W | 24 |
| 7 | 2022-11-26 | Chicago State (323) | 68 | 82 | Marquette (14) | Final | W | 14 |
| 8 | 2022-11-29 | Baylor (9) | 70 | 96 | Marquette (14) | Final | W | 26 |
| 9 | 2022-12-03 | Wisconsin (24) | 80 | 77 | Marquette (106) | Final/OT | L | -3 |
| 10 | 2022-12-06 | North Carolina Central (341) | 78 | 90 | Marquette (106) | Final | W | 12 |
| 11 | 2022-12-11 | Marquette (14) | 79 | 64 | Notre Dame (199) | Final | W | 15 |
| 12 | 2022-12-16 | Creighton (78) | 58 | 69 | Marquette (106) | Final | W | 11 |
| 13 | 2022-12-20 | Marquette (14) | 98 | 103 | Providence (31) | Final | L | -5 |
| 14 | 2022-12-27 | Seton Hall (73) | 69 | 83 | Marquette (14) | Final | W | 14 |
| 15 | 2022-12-31 | Marquette (14) | 68 | 66 | Villanova (93) | Final | W | 2 |
| 16 | 2023-01-03 | Marquette (14) | 96 | 85 | St. John's (85) | Final | W | 11 |
| 17 | 2023-01-07 | Georgetown (215) | 73 | 95 | Marquette (14) | Final | W | 22 |
| 18 | 2023-01-11 | Connecticut (13) | 76 | 82 | Marquette (14) | Final | W | 6 |
| 19 | 2023-01-15 | Marquette (14) | 76 | 80 | Xavier (18) | Final | L | -4 |
| 20 | 2023-01-18 | Providence (31) | 75 | 83 | Marquette (14) | Final | W | 8 |
| 21 | 2023-01-21 | Marquette (14) | 74 | 53 | Seton Hall (73) | Final | W | 21 |
| 22 | 2023-01-28 | Marquette (14) | 89 | 69 | DePaul (159) | Final | W | 20 |
| 23 | 2023-02-01 | Villanova (93) | 64 | 73 | Marquette (14) | Final | W | 9 |
| 24 | 2023-02-04 | Butler (104) | 52 | 60 | Marquette (14) | Final | W | 8 |
| 25 | 2023-02-07 | Marquette (14) | 72 | 87 | Connecticut (13) | Final | L | -15 |
| 26 | 2023-02-11 | Marquette (106) | 89 | 75 | Georgetown (83) | Final | W | 14 |
| 27 | 2023-02-15 | Xavier (92) | 68 | 69 | Marquette (106) | Final | W | 1 |
| 28 | 2023-02-21 | Marquette (14) | 73 | 71 | Creighton (21) | Final | W | 2 |
| 29 | 2023-02-25 | DePaul (163) | 84 | 90 | Marquette (13) | Final | W | 6 |
| 30 | 2023-02-28 | Marquette (13) | 72 | 56 | Butler (104) | Final | W | 16 |
| 31 | 2023-03-04 | St. John's (12) | 94 | 96 | Marquette (106) | Final | W | 2 |
| 32 | 2023-03-09 | St. John's (86) | 70 | 72 | Marquette (11) | Final | W | 2 |
| 33 | 2023-03-10 | Connecticut (8) | 68 | 70 | Marquette (11) | Final | W | 2 |
| 34 | 2023-03-11 | Xavier (18) | 51 | 65 | Marquette (8) | Final | W | 14 |
| 35 | 2023-03-17 | Vermont | 61 | 78 | Marquette | Final | W | 17 |
| 36 | 2023-03-19 | Michigan State (38) | 69 | 60 | Marquette (9) | Final | L | -9 |