Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Merrimack (304) | 72 | 97 | St. John's (85) | Final | W | 25 |
| 2 | 2022-11-12 | Lafayette (298) | 68 | 83 | St. John's (85) | Final | W | 15 |
| 3 | 2022-11-15 | Central Connecticut State (330) | 74 | 91 | St. John's (85) | Final | W | 17 |
| 4 | 2022-11-17 | Nebraska (83) | 50 | 70 | St. John's (85) | Final | W | 20 |
| 5 | 2022-11-21 | St. John's (85) | 78 | 72 | Temple (108) | Final | W | 6 |
| 6 | 2022-11-23 | Syracuse (87) | 69 | 76 | St. John's (85) | Final | W | 7 |
| 7 | 2022-11-26 | Niagara (229) | 70 | 78 | St. John's (85) | Final | W | 8 |
| 8 | 2022-11-29 | Long Island (363) | 68 | 95 | St. John's (85) | Final | W | 27 |
| 9 | 2022-12-04 | St. John's (85) | 60 | 71 | Iowa State (20) | Final | L | -11 |
| 10 | 2022-12-07 | DePaul (159) | 67 | 86 | St. John's (85) | Final | W | 19 |
| 11 | 2022-12-10 | New Hampshire (260) | 51 | 64 | St. John's (85) | Final | W | 13 |
| 12 | 2022-12-17 | St. John's (85) | 93 | 79 | Florida State (209) | Final | W | 14 |
| 13 | 2022-12-21 | St. John's (85) | 63 | 78 | Villanova (93) | Final | L | -15 |
| 14 | 2022-12-28 | Xavier (18) | 84 | 79 | St. John's (85) | Final | L | -5 |
| 15 | 2022-12-31 | St. John's (85) | 66 | 88 | Seton Hall (73) | Final | L | -22 |
| 16 | 2023-01-03 | Marquette (14) | 96 | 85 | St. John's (85) | Final | L | -11 |
| 17 | 2023-01-07 | St. John's (85) | 80 | 83 | Providence (31) | Final | L | -3 |
| 18 | 2023-01-10 | Butler (104) | 61 | 77 | St. John's (85) | Final | W | 16 |
| 19 | 2023-01-15 | St. John's (85) | 85 | 74 | Connecticut (13) | Final | W | 11 |
| 20 | 2023-01-20 | Villanova (93) | 57 | 49 | St. John's (85) | Final | L | -8 |
| 21 | 2023-01-25 | St. John's (85) | 76 | 104 | Creighton (21) | Final | L | -28 |
| 22 | 2023-01-29 | Georgetown (215) | 73 | 75 | St. John's (85) | Final | W | 2 |
| 23 | 2023-02-01 | Seton Hall (73) | 84 | 72 | St. John's (85) | Final | L | -12 |
| 24 | 2023-02-04 | St. John's (85) | 71 | 96 | Xavier (18) | Final | L | -25 |
| 25 | 2023-02-07 | St. John's (85) | 66 | 68 | Butler (104) | Final | L | -2 |
| 26 | 2023-02-11 | Providence (31) | 68 | 73 | St. John's (85) | Final | W | 5 |
| 27 | 2023-02-14 | St. John's (85) | 92 | 83 | DePaul (159) | Final | W | 9 |
| 28 | 2023-02-18 | Creighton (21) | 77 | 67 | St. John's (85) | Final | L | -10 |
| 29 | 2023-02-22 | St. John's (84) | 79 | 70 | Georgetown (221) | Final | W | 9 |
| 30 | 2023-02-25 | Connecticut (12) | 95 | 86 | St. John's (88) | Final | L | -9 |
| 31 | 2023-03-04 | St. John's (91) | 94 | 96 | Marquette (12) | Final | L | -2 |
| 32 | 2023-03-08 | Butler (114) | 63 | 76 | St. John's (84) | Final | W | 13 |
| 33 | 2023-03-09 | St. John's (86) | 70 | 72 | Marquette (11) | Final | L | -2 |