Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-03 | Fairleigh Dickinson (319) | 50 | 88 | Iowa State (19) | Final | W | 38 |
| 2 | 2025-11-06 | Grambling (336) | 62 | 102 | Iowa State (19) | Final | W | 40 |
| 3 | 2025-11-10 | Mississippi State (30) | 80 | 96 | Iowa State (19) | Final | W | 16 |
| 4 | 2025-11-17 | Stonehill (310) | 57 | 96 | Iowa State (19) | Final | W | 39 |
| 5 | 2025-11-24 | Iowa State (19) | 83 | 82 | St. John’s (8) | Final | W | 1 |
| 6 | 2025-11-25 | Creighton (32) | 60 | 78 | Iowa State (19) | Final | W | 18 |
| 7 | 2025-11-26 | Syracuse (121) | 64 | 95 | Iowa State (19) | Final | W | 31 |
| 8 | 2025-12-03 | Alcorn State (338) | 68 | 132 | Iowa State (12) | Final | W | 64 |
| 9 | 2025-12-06 | Iowa State (12) | 81 | 58 | Purdue (3) | Final | W | 23 |
| 10 | 2025-12-11 | Iowa (23) | 62 | 66 | Iowa State (5) | Final | W | 4 |
| 11 | 2025-12-14 | Eastern Illinois (337) | 53 | 78 | Iowa State (4) | Final | W | 25 |
| 12 | 2025-12-21 | Long Beach State (293) | 60 | 91 | Iowa State (3) | Final | W | 31 |
| 13 | 2025-12-29 | Houston Christian (317) | 61 | 89 | Iowa State (3) | Final | W | 28 |
| 14 | 2026-01-02 | West Virginia (105) | 59 | 80 | Iowa State (3) | Final | W | 21 |
| 15 | 2026-01-07 | Iowa State | Baylor | Scheduled – 7:00 PM | – | – | ||
| 16 | 2026-01-10 | Oklahoma State | Iowa State | Scheduled – 3:00 PM | – | – | ||
| 17 | 2026-01-13 | Iowa State | Kansas | Scheduled – 8:00 PM | – | – | ||
| 18 | 2026-01-17 | Iowa State | Cincinnati | Scheduled – 2:00 PM | – | – | ||
| 19 | 2026-01-20 | Central Florida | Iowa State | Scheduled – 6:00 PM | – | – | ||
| 20 | 2026-01-24 | Iowa State | Oklahoma State | Scheduled – 3:00 PM | – | – | ||
| 21 | 2026-01-29 | Colorado | Iowa State | Scheduled – 6:00 PM | – | – | ||
| 22 | 2026-02-01 | Iowa State | Kansas State | Scheduled – 1:00 PM | – | – | ||
| 23 | 2026-02-07 | Baylor | Iowa State | Scheduled – 1:00 PM | – | – | ||
| 24 | 2026-02-10 | Iowa State | TCU | Scheduled – 8:00 PM | – | – | ||
| 25 | 2026-02-14 | Kansas | Iowa State | Scheduled – 12:00 PM | – | – | ||
| 26 | 2026-02-16 | Houston | Iowa State | Scheduled – 8:00 PM | – | – | ||
| 27 | 2026-02-21 | Iowa State | BYU | Scheduled – 8:30 PM | – | – | ||
| 28 | 2026-02-24 | Iowa State | Utah | Scheduled – 7:00 PM | – | – | ||
| 29 | 2026-02-28 | Texas Tech | Iowa State | Scheduled – 3:00 PM | – | – | ||
| 30 | 2026-03-02 | Iowa State | Arizona | Scheduled – 7:00 PM | – | – | ||
| 31 | 2026-03-07 | Arizona State | Iowa State | Scheduled – 1:00 PM | – | – |