NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | St. Francis (NY) (280) | 66 | 74 | Manhattan (178) | Final | W | 8 |
| 2 | 2021-11-11 | Manhattan | Dartmouth | Cancelled | - | - | ||
| 3 | 2021-11-13 | Army (230) | 55 | 75 | Manhattan (178) | Final | W | 20 |
| 4 | 2021-11-19 | Florida Gulf Coast (20) | 88 | 57 | Manhattan (73) | Final | L | -31 |
| 5 | 2021-11-20 | Manhattan (73) | 55 | 57 | Stetson (172) | Final | L | -2 |
| 6 | 2021-11-24 | Manhattan (166) | 61 | 52 | Long Island (327) | Final | W | 9 |
| 7 | 2021-11-28 | Fairleigh Dickinson (275) | 55 | 69 | Manhattan (166) | Final | W | 14 |
| 8 | 2021-12-01 | Manhattan (116) | 50 | 54 | Wagner (167) | Final | L | -4 |
| 9 | 2021-12-08 | Manhattan (143) | 63 | 65 | Fordham (51) | Final | L | -2 |
| 10 | 2021-12-11 | Manhattan (143) | 56 | 44 | Dartmouth (352) | Final | W | 12 |
| 11 | 2021-12-19 | Manhattan (296) | 70 | 73 | Niagara (362) | Final | L | -3 |
| 12 | 2021-12-21 | Manhattan (189) | 85 | 63 | Canisius (338) | Final | W | 22 |
| 13 | 2021-12-30 | Siena (350) | 0 | 0 | Manhattan (183) | Postponed | - | - |
| 14 | 2022-01-01 | Manhattan (183) | 0 | 0 | Saint Peter's (240) | Postponed | - | - |
| 15 | 2022-01-06 | Rider (280) | 58 | 63 | Manhattan (185) | Final | W | 5 |
| 16 | 2022-01-08 | Marist (300) | 45 | 72 | Manhattan (296) | Final | W | 27 |
| 17 | 2022-01-13 | Iona (251) | 59 | 64 | Manhattan (296) | Final | W | 5 |
| 18 | 2022-01-15 | Manhattan (173) | 47 | 53 | Siena (345) | Final | L | -6 |
| 19 | 2022-01-20 | Manhattan (183) | 55 | 70 | Fairfield (126) | Final | L | -15 |
| 20 | 2022-01-22 | Manhattan (183) | 65 | 72 | Quinnipiac (157) | Final | L | -7 |
| 21 | 2022-01-25 | Manhattan (207) | 66 | 56 | Saint Peter's (259) | Final | W | 10 |
| 22 | 2022-01-27 | Manhattan (296) | 71 | 69 | Iona (251) | Final | W | 2 |
| 23 | 2022-01-30 | Monmouth (192) | 57 | 73 | Manhattan (207) | Final | W | 16 |
| 24 | 2022-02-03 | Saint Peter's (257) | 45 | 65 | Manhattan (181) | Final | W | 20 |
| 25 | 2022-02-05 | Niagara (362) | 85 | 73 | Manhattan (296) | Final | L | -12 |
| 26 | 2022-02-10 | Manhattan (296) | 56 | 49 | Rider (339) | Final | W | 7 |
| 27 | 2022-02-14 | Siena (298) | 61 | 69 | Manhattan (190) | Final | W | 8 |
| 28 | 2022-02-17 | Canisius (336) | 62 | 86 | Manhattan (186) | Final | W | 24 |
| 29 | 2022-02-19 | Manhattan (186) | 73 | 63 | Monmouth (217) | Final | W | 10 |
| 30 | 2022-02-26 | Fairfield (113) | 75 | 63 | Manhattan (178) | Final | L | -12 |
| 31 | 2022-03-02 | Quinnipiac (154) | 69 | 73 | Manhattan (184) | Final/OT | W | 4 |
| 32 | 2022-03-05 | Manhattan (184) | 68 | 60 | Marist (293) | Final/OT | W | 8 |
| 33 | 2022-03-10 | Canisius (331) | 49 | 61 | Manhattan (175) | Final | W | 12 |
| 34 | 2022-03-11 | Manhattan (175) | 72 | 59 | Quinnipiac (164) | Final | W | 13 |
| 35 | 2022-03-12 | Manhattan (175) | 68 | 73 | Fairfield (98) | Final | L | -5 |