NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Arizona Christian | 48 | 95 | Grand Canyon (125) | Final | W | 47 |
| 2 | 2021-11-16 | Eastern Washington (346) | 57 | 64 | Grand Canyon (156) | Final | W | 7 |
| 3 | 2021-11-20 | Grand Canyon (156) | 62 | 89 | UMKC (210) | Final | L | -27 |
| 4 | 2021-11-26 | Nicholls State (273) | 55 | 103 | Grand Canyon (176) | Final | W | 48 |
| 5 | 2021-11-27 | Houston Baptist (250) | 54 | 63 | Grand Canyon (202) | Final | W | 9 |
| 6 | 2021-12-01 | Park | 48 | 98 | Grand Canyon (128) | Final | W | 50 |
| 7 | 2021-12-04 | Grand Canyon (176) | 53 | 60 | Cal State-Fullerton (200) | Final | L | -7 |
| 8 | 2021-12-09 | Grand Canyon (165) | 77 | 108 | Northern Arizona (120) | Final | L | -31 |
| 9 | 2021-12-17 | Liberty (60) | 76 | 61 | Grand Canyon (207) | Final | L | -15 |
| 10 | 2021-12-18 | UTSA (120) | 52 | 62 | Grand Canyon (176) | Final | W | 10 |
| 11 | 2021-12-23 | UC-Irvine (169) | 53 | 58 | Grand Canyon (197) | Final | W | 5 |
| 12 | 2021-12-30 | Grand Canyon (180) | 66 | 49 | Chicago State (329) | Final | W | 17 |
| 13 | 2022-01-06 | UTRGV (262) | 62 | 50 | Grand Canyon (178) | Final | L | -12 |
| 14 | 2022-01-08 | Lamar (186) | 72 | 73 | Grand Canyon (176) | Final/OT | W | 1 |
| 15 | 2022-01-13 | Grand Canyon (176) | 74 | 69 | Abilene Christian (137) | Final | W | 5 |
| 16 | 2022-01-15 | Grand Canyon (189) | 47 | 37 | Tarleton State (192) | Final | W | 10 |
| 17 | 2022-01-20 | Stephen F. Austin (48) | 0 | 0 | Grand Canyon (162) | Postponed | - | - |
| 18 | 2022-01-22 | Sam Houston State (291) | 54 | 73 | Grand Canyon (162) | Final | W | 19 |
| 19 | 2022-01-29 | New Mexico State (200) | 59 | 61 | Grand Canyon (166) | Final | W | 2 |
| 20 | 2022-01-31 | Stephen F. Austin (159) | 61 | 43 | Grand Canyon (176) | Final | L | -18 |
| 21 | 2022-02-03 | Grand Canyon (157) | 64 | 59 | Seattle (285) | Final | W | 5 |
| 22 | 2022-02-05 | Grand Canyon (176) | 61 | 52 | California Baptist (130) | Final | W | 9 |
| 23 | 2022-02-10 | Utah Valley (216) | 58 | 50 | Grand Canyon (176) | Final | L | -8 |
| 24 | 2022-02-12 | Dixie State (307) | 50 | 66 | Grand Canyon (140) | Final | W | 16 |
| 25 | 2022-02-17 | California Baptist (100) | 55 | 75 | Grand Canyon (160) | Final | W | 20 |
| 26 | 2022-02-19 | Grand Canyon (160) | 46 | 43 | New Mexico State (250) | Final | W | 3 |
| 27 | 2022-02-24 | Chicago State (315) | 55 | 73 | Grand Canyon (138) | Final | W | 18 |
| 28 | 2022-02-26 | Grand Canyon (138) | 66 | 69 | Sam Houston State (231) | Final | L | -3 |
| 29 | 2022-03-03 | Grand Canyon (151) | 65 | 63 | Utah Valley (201) | Final | W | 2 |
| 30 | 2022-03-05 | Grand Canyon (151) | 65 | 59 | Dixie State (301) | Final | W | 6 |
| 31 | 2022-03-11 | California Baptist (107) | 60 | 64 | Grand Canyon (146) | Final | W | 4 |
| 32 | 2022-03-12 | Grand Canyon (146) | 57 | 74 | Stephen F. Austin (56) | Final | L | -17 |
| 33 | 2022-03-16 | Grand Canyon (136) | 72 | 92 | New Mexico (99) | Final | L | -20 |