NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-11 | Wiley | 62 | 86 | Sam Houston State (162) | Final | W | 24 |
| 2 | 2021-11-13 | Sam Houston State (146) | 54 | 72 | Texas-Arlington (164) | Final | L | -18 |
| 3 | 2021-11-15 | Sam Houston State (146) | 48 | 64 | Tulsa (206) | Final | L | -16 |
| 4 | 2021-11-17 | Science and Arts of Oklahoma | 73 | 88 | Sam Houston State (315) | Final | W | 15 |
| 5 | 2021-11-20 | Hartford (308) | 65 | 88 | Sam Houston State (315) | Final | W | 23 |
| 6 | 2021-11-27 | Sam Houston State (254) | 66 | 92 | Arkansas (39) | Final | L | -26 |
| 7 | 2021-11-30 | Longwood (149) | 65 | 66 | Sam Houston State (259) | Final | W | 1 |
| 8 | 2021-12-10 | Sam Houston State (207) | 52 | 77 | Louisiana Tech (139) | Final | L | -25 |
| 9 | 2021-12-13 | Sam Houston State (207) | 50 | 84 | Alabama (44) | Final | L | -34 |
| 10 | 2021-12-16 | Rice (188) | 74 | 64 | Sam Houston State (254) | Final | L | -10 |
| 11 | 2021-12-20 | Arlington Baptist | 55 | 132 | Sam Houston State (254) | Final | W | 77 |
| 12 | 2021-12-30 | Sam Houston State (253) | 0 | 0 | Lamar (206) | Postponed | - | - |
| 13 | 2022-01-01 | Sam Houston State (253) | 0 | 0 | UTRGV (263) | Postponed | - | - |
| 14 | 2022-01-06 | Tarleton State (179) | 0 | 0 | Sam Houston State (259) | Postponed | - | - |
| 15 | 2022-01-08 | Abilene Christian (137) | 70 | 59 | Sam Houston State (162) | Final | L | -11 |
| 16 | 2022-01-13 | Lamar (186) | 68 | 55 | Sam Houston State (162) | Final | L | -13 |
| 17 | 2022-01-15 | Sam Houston State (268) | 46 | 79 | Stephen F. Austin (50) | Final | L | -33 |
| 18 | 2022-01-17 | Tarleton State (192) | 62 | 61 | Sam Houston State (268) | Final | L | -1 |
| 19 | 2022-01-20 | Sam Houston State (291) | 59 | 72 | New Mexico State (213) | Final | L | -13 |
| 20 | 2022-01-22 | Sam Houston State (291) | 54 | 73 | Grand Canyon (162) | Final | L | -19 |
| 21 | 2022-01-24 | Sam Houston State (291) | 66 | 52 | UTRGV (228) | Final | W | 14 |
| 22 | 2022-01-27 | California Baptist (130) | 65 | 73 | Sam Houston State (162) | Final | W | 8 |
| 23 | 2022-01-29 | Seattle (271) | 54 | 73 | Sam Houston State (290) | Final | W | 19 |
| 24 | 2022-02-03 | Sam Houston State (258) | 74 | 72 | Dixie State (303) | Final/OT | W | 2 |
| 25 | 2022-02-05 | Sam Houston State (162) | 69 | 66 | Utah Valley (216) | Final | W | 3 |
| 26 | 2022-02-12 | Chicago State (308) | 58 | 61 | Sam Houston State (245) | Final | W | 3 |
| 27 | 2022-02-14 | Sam Houston State (245) | 66 | 57 | Lamar (187) | Final | W | 9 |
| 28 | 2022-02-17 | Sam Houston State (237) | 71 | 88 | Abilene Christian (189) | Final | L | -17 |
| 29 | 2022-02-19 | UTRGV (244) | 49 | 69 | Sam Houston State (237) | Final | W | 20 |
| 30 | 2022-02-24 | Stephen F. Austin (48) | 73 | 58 | Sam Houston State (231) | Final | L | -15 |
| 31 | 2022-02-26 | Grand Canyon (138) | 66 | 69 | Sam Houston State (231) | Final | W | 3 |
| 32 | 2022-03-02 | Sam Houston State (219) | 63 | 83 | Tarleton State (239) | Final | L | -20 |
| 33 | 2022-03-09 | Lamar (212) | 69 | 73 | Sam Houston State (227) | Final | W | 4 |
| 34 | 2022-03-10 | Sam Houston State (227) | 78 | 85 | California Baptist (107) | Final | L | -7 |