Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-03 | Northern Illinois | 34 | Wyoming | 40 | Final/3OT | W | 6 |
| 2 | 2016-09-10 | Wyoming (114) | 17 | Nebraska (47) | 52 | Final | L | -35 |
| 3 | 2016-09-17 | UC-Davis | 22 | Wyoming | 45 | Final | W | 23 |
| 4 | 2016-09-23 | Wyoming | 24 | Eastern Michigan | 27 | Final | L | -3 |
| 5 | 2016-10-01 | Wyoming (101) | 38 | Colorado State (82) | 17 | Final | W | 21 |
| 6 | 2016-10-08 | Air Force (20) | 26 | Wyoming (87) | 35 | Final | W | 9 |
| 7 | 2016-10-22 | Wyoming (25) | 42 | Nevada (118) | 34 | Final | W | 8 |
| 8 | 2016-10-29 | Boise State (9) | 28 | Wyoming (30) | 30 | Final | W | 2 |
| 9 | 2016-11-05 | Utah State (96) | 28 | Wyoming (21) | 52 | Final | W | 24 |
| 10 | 2016-11-12 | Wyoming (16) | 66 | UNLV (114) | 69 | Final/3OT | L | -3 |
| 11 | 2016-11-19 | San Diego State (29) | 33 | Wyoming (35) | 34 | Final | W | 1 |
| 12 | 2016-11-26 | Wyoming (29) | 35 | New Mexico (74) | 56 | Final | L | -21 |
| 13 | 2016-12-03 | San Diego State (48) | 27 | Wyoming (43) | 24 | Final | L | -3 |
| 14 | 2016-12-21 | BYU (46) | 24 | Wyoming (47) | 21 | Final | L | -3 |