Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-09-05 | William Jewell | 30 | Drake | 44 | Final | W | 14 |
| 2 | 2015-09-12 | Drake | 18 | North Dakota | 21 | Final | L | -3 |
| 3 | 2015-09-19 | Drake | 0 | South Dakota | 52 | Final | L | -52 |
| 4 | 2015-09-26 | Stetson | 3 | Drake | 41 | Final | W | 38 |
| 5 | 2015-10-03 | Drake | 14 | Campbell | 24 | Final | L | -10 |
| 6 | 2015-10-10 | Valparaiso | 7 | Drake | 34 | Final | W | 27 |
| 7 | 2015-10-17 | Drake | 0 | San Diego | 27 | Final | L | -27 |
| 8 | 2015-10-24 | Jacksonville | 24 | Drake | 28 | Final | W | 4 |
| 9 | 2015-10-31 | Drake | 35 | Morehead State | 38 | Final/OT | L | -3 |
| 10 | 2015-11-14 | Drake | 13 | Butler | 20 | Final | L | -7 |
| 11 | 2015-11-21 | Dayton | 17 | Drake | 27 | Final | W | 10 |