Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-08-30 | Missouri State (206) | 17 | Oklahoma State (21) | 58 | Final | L | -41 |
| 2 | 2018-09-06 | Lincoln (MO) | 24 | Missouri State | 52 | Final | W | 28 |
| 3 | 2018-09-15 | Northern Arizona | 8 | Missouri State | 40 | Final | W | 32 |
| 4 | 2018-09-29 | Illinois State (111) | 21 | Missouri State (158) | 24 | Final | W | 3 |
| 5 | 2018-10-06 | Missouri State (140) | 28 | South Dakota (176) | 35 | Final | L | -7 |
| 6 | 2018-10-13 | Missouri State (150) | 29 | Indiana State (200) | 26 | Final | W | 3 |
| 7 | 2018-10-20 | Western Illinois (177) | 31 | Missouri State (152) | 14 | Final | L | -17 |
| 8 | 2018-10-27 | Southern Illinois (224) | 49 | Missouri State (170) | 35 | Final | L | -14 |
| 9 | 2018-11-03 | Missouri State (181) | 7 | South Dakota State (129) | 59 | Final | L | -52 |
| 10 | 2018-11-10 | North Dakota State (83) | 48 | Missouri State (192) | 7 | Final | L | -41 |
| 11 | 2018-11-17 | Missouri State (201) | 0 | Northern Iowa (154) | 37 | Final | L | -37 |