Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | St. Xavier (IL) | 0 | Illinois State | 46 | Final | W | 46 |
| 2 | 2018-09-08 | Eastern Illinois | 10 | Illinois State | 48 | Final | W | 38 |
| 3 | 2018-09-22 | Illinois State (154) | 35 | Colorado State (87) | 19 | Final | W | 16 |
| 4 | 2018-09-29 | Illinois State (111) | 21 | Missouri State (158) | 24 | Final | L | -3 |
| 5 | 2018-10-06 | Western Illinois (165) | 16 | Illinois State (134) | 33 | Final | W | 17 |
| 6 | 2018-10-13 | Southern Illinois (216) | 3 | Illinois State (133) | 51 | Final | W | 48 |
| 7 | 2018-10-20 | Illinois State (123) | 14 | North Dakota State (98) | 28 | Final | L | -14 |
| 8 | 2018-10-27 | South Dakota State (138) | 38 | Illinois State (127) | 28 | Final | L | -10 |
| 9 | 2018-11-03 | Illinois State (136) | 16 | Northern Iowa (156) | 26 | Final | L | -10 |
| 10 | 2018-11-10 | Illinois State (147) | 23 | Indiana State (183) | 28 | Final | L | -5 |
| 11 | 2018-11-17 | Youngstown State (189) | 28 | Illinois State (159) | 35 | Final | W | 7 |