Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-08-30 | Missouri State (206) | 17 | Oklahoma State (21) | 58 | Final | W | 41 |
| 2 | 2018-09-08 | South Alabama (119) | 13 | Oklahoma State (21) | 55 | Final | W | 42 |
| 3 | 2018-09-15 | Boise State (25) | 21 | Oklahoma State (21) | 44 | Final | W | 23 |
| 4 | 2018-09-22 | Texas Tech (63) | 41 | Oklahoma State (21) | 17 | Final | L | -24 |
| 5 | 2018-09-29 | Oklahoma State (32) | 48 | Kansas (95) | 28 | Final | W | 20 |
| 6 | 2018-10-06 | Iowa State (75) | 48 | Oklahoma State (26) | 42 | Final | L | -6 |
| 7 | 2018-10-13 | Oklahoma State (54) | 12 | Kansas State (92) | 31 | Final | L | -19 |
| 8 | 2018-10-27 | Texas (13) | 35 | Oklahoma State (67) | 38 | Final | W | 3 |
| 9 | 2018-11-03 | Oklahoma State (52) | 31 | Baylor (81) | 35 | Final | L | -4 |
| 10 | 2018-11-10 | Oklahoma State (61) | 47 | Oklahoma (6) | 48 | Final | L | -1 |
| 11 | 2018-11-17 | West Virginia (10) | 41 | Oklahoma State (62) | 45 | Final | W | 4 |
| 12 | 2018-11-24 | Oklahoma State (50) | 24 | TCU (64) | 31 | Final | L | -7 |
| 13 | 2018-12-31 | Missouri (15) | 33 | Oklahoma State (54) | 38 | Final | W | 5 |