Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | Utah (22) | 26 | Florida (67) | 29 | Final | W | 3 |
| 2 | 2022-09-10 | Kentucky (24) | 26 | Florida (67) | 16 | Final | L | -10 |
| 3 | 2022-09-17 | South Florida (105) | 28 | Florida (41) | 31 | Final | W | 3 |
| 4 | 2022-09-24 | Florida (53) | 33 | Tennessee (6) | 38 | Final | L | -5 |
| 5 | 2022-10-02 | Eastern Washington (202) | 17 | Florida (93) | 52 | Final | W | 35 |
| 6 | 2022-10-08 | Missouri (81) | 17 | Florida (42) | 24 | Final | W | 7 |
| 7 | 2022-10-15 | LSU (21) | 45 | Florida (42) | 35 | Final | L | -10 |
| 8 | 2022-10-29 | Florida (43) | 20 | Georgia (3) | 42 | Final | L | -22 |
| 9 | 2022-11-05 | Florida (38) | 41 | Texas A&M (96) | 24 | Final | W | 17 |
| 10 | 2022-11-12 | South Carolina (61) | 6 | Florida (26) | 38 | Final | W | 32 |
| 11 | 2022-11-19 | Florida (40) | 24 | Vanderbilt (73) | 31 | Final | L | -7 |
| 12 | 2022-11-25 | Florida (39) | 38 | Florida State (15) | 45 | Final | L | -7 |
| 13 | 2022-12-17 | Florida (36) | 3 | Oregon State (17) | 30 | Final | L | -27 |