Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-03 | Butler | 25 | Indiana State | 41 | Final | L | -16 |
| 2 | 2016-09-10 | Franklin | 14 | Butler | 59 | Final | W | 45 |
| 3 | 2016-09-17 | Butler | 27 | Taylor | 14 | Final | W | 13 |
| 4 | 2016-09-24 | Butler | 27 | Campbell | 33 | Final/OT | L | -6 |
| 5 | 2016-10-01 | San Diego | 44 | Butler | 10 | Final | L | -34 |
| 6 | 2016-10-08 | Marist | 30 | Butler | 21 | Final | L | -9 |
| 7 | 2016-10-15 | Butler | 20 | Davidson | 17 | Final | W | 3 |
| 8 | 2016-10-22 | Dayton | 31 | Butler | 16 | Final | L | -15 |
| 9 | 2016-10-29 | Butler (237) | 23 | Valparaiso (238) | 12 | Final | W | 11 |
| 10 | 2016-11-05 | Morehead State (238) | 54 | Butler (231) | 28 | Final | L | -26 |
| 11 | 2016-11-12 | Butler (239) | 14 | Drake (214) | 28 | Final | L | -14 |