Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-10 | Akron (158) | 0 | Michigan State (10) | 52 | Final | L | -52 |
| 2 | 2022-09-17 | Akron (120) | 6 | Tennessee (3) | 63 | Final | L | -57 |
| 3 | 2022-09-24 | Akron (119) | 12 | Liberty (30) | 21 | Final | L | -9 |
| 4 | 2022-10-01 | Bowling Green (101) | 31 | Akron (134) | 28 | Final | L | -3 |
| 5 | 2022-10-08 | Akron (146) | 34 | Ohio (103) | 55 | Final | L | -21 |
| 6 | 2022-10-15 | Central Michigan (112) | 28 | Akron (152) | 21 | Final | L | -7 |
| 7 | 2022-10-22 | Akron (157) | 27 | Kent State (103) | 33 | Final | L | -6 |
| 8 | 2022-10-29 | Miami (OH) (114) | 27 | Akron (163) | 9 | Final | L | -18 |
| 9 | 2022-11-08 | Eastern Michigan (115) | 34 | Akron (162) | 28 | Final | L | -6 |
| 10 | 2022-11-26 | Akron (151) | 44 | Northern Illinois (137) | 12 | Final | W | 32 |
| 11 | 2022-12-02 | Akron (152) | 22 | Buffalo (101) | 23 | Final | L | -1 |