Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-11-10 | Morehead State (205) | 49 | 101 | Xavier (36) | Final | W | 52 |
| 2 | 2017-11-13 | Rider (211) | 75 | 101 | Xavier (36) | Final | W | 26 |
| 3 | 2017-11-16 | Xavier (36) | 80 | 70 | Wisconsin (21) | Final | W | 10 |
| 4 | 2017-11-20 | Hampton (307) | 60 | 96 | Xavier (36) | Final | W | 36 |
| 5 | 2017-11-23 | George Washington (167) | 64 | 83 | Xavier (4) | Final | W | 19 |
| 6 | 2017-11-24 | Arizona State (14) | 102 | 86 | Xavier (4) | Final | L | -16 |
| 7 | 2017-11-28 | Baylor (15) | 63 | 76 | Xavier (21) | Final | W | 13 |
| 8 | 2017-12-02 | Cincinnati (10) | 76 | 89 | Xavier (21) | Final | W | 13 |
| 9 | 2017-12-06 | Kent State (185) | 70 | 96 | Xavier (12) | Final | W | 26 |
| 10 | 2017-12-09 | Colorado (74) | 69 | 96 | Xavier (12) | Final | W | 27 |
| 11 | 2017-12-16 | East Tennessee State (140) | 66 | 68 | Xavier (7) | Final | W | 2 |
| 12 | 2017-12-19 | Marshall (139) | 77 | 81 | Xavier (7) | Final | W | 4 |
| 13 | 2017-12-22 | Xavier (7) | 77 | 67 | Northern Iowa (47) | Final | W | 10 |
| 14 | 2017-12-27 | Xavier (6) | 91 | 87 | Marquette (52) | Final | W | 4 |
| 15 | 2017-12-30 | DePaul (127) | 72 | 77 | Xavier (6) | Final | W | 5 |
| 16 | 2018-01-02 | Butler (22) | 79 | 86 | Xavier (4) | Final | W | 7 |
| 17 | 2018-01-06 | Xavier (4) | 72 | 81 | Providence (64) | Final | L | -9 |
| 18 | 2018-01-10 | Xavier (9) | 65 | 89 | Villanova (4) | Final | L | -24 |
| 19 | 2018-01-13 | Creighton (20) | 70 | 92 | Xavier (9) | Final | W | 22 |
| 20 | 2018-01-17 | St. John's (84) | 82 | 88 | Xavier (11) | Final | W | 6 |
| 21 | 2018-01-20 | Xavier (11) | 73 | 64 | Seton Hall (18) | Final | W | 9 |
| 22 | 2018-01-24 | Marquette (37) | 70 | 89 | Xavier (6) | Final | W | 19 |
| 23 | 2018-01-30 | Xavier (5) | 73 | 68 | St. John's (101) | Final | W | 5 |
| 24 | 2018-02-03 | Georgetown (95) | 91 | 96 | Xavier (5) | Final/OT | W | 5 |
| 25 | 2018-02-06 | Xavier (4) | 98 | 93 | Butler (23) | Final/OT | W | 5 |
| 26 | 2018-02-10 | Xavier (4) | 72 | 71 | Creighton (19) | Final | W | 1 |
| 27 | 2018-02-14 | Seton Hall (32) | 90 | 102 | Xavier (4) | Final | W | 12 |
| 28 | 2018-02-17 | Villanova (1) | 95 | 79 | Xavier (4) | Final | L | -16 |
| 29 | 2018-02-21 | Xavier (4) | 89 | 77 | Georgetown (86) | Final | W | 12 |
| 30 | 2018-02-28 | Providence (55) | 74 | 84 | Xavier (5) | Final | W | 10 |
| 31 | 2018-03-03 | Xavier (5) | 65 | 62 | DePaul (116) | Final | W | 3 |
| 32 | 2018-03-08 | St. John's (73) | 60 | 88 | Xavier (4) | Final | W | 28 |
| 33 | 2018-03-09 | Providence (57) | 75 | 72 | Xavier (4) | Final/OT | L | -3 |
| 34 | 2018-03-16 | Texas Southern (217) | 83 | 102 | Xavier (42) | Final - 0:00 | W | 19 |
| 35 | 2018-03-18 | Florida State (96) | 75 | 70 | Xavier (42) | Final - 0:00 | L | -5 |