Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-11-11 | Notre Dame (18) | 72 | 58 | DePaul (182) | Final | L | -14 |
| 2 | 2017-11-13 | Delaware State (338) | 57 | 81 | DePaul (182) | Final | W | 24 |
| 3 | 2017-11-17 | DePaul (182) | 73 | 82 | Illinois (55) | Final | L | -9 |
| 4 | 2017-11-23 | Michigan State (120) | 73 | 51 | DePaul (197) | Final | L | -22 |
| 5 | 2017-11-24 | Oregon (39) | 89 | 79 | DePaul (197) | Final/OT | L | -10 |
| 6 | 2017-11-26 | Portland (211) | 69 | 82 | DePaul (197) | Final | W | 13 |
| 7 | 2017-12-02 | Youngstown State (330) | 73 | 89 | DePaul (188) | Final | W | 16 |
| 8 | 2017-12-06 | Central Connecticut State (179) | 57 | 85 | DePaul (190) | Final | W | 28 |
| 9 | 2017-12-09 | DePaul (190) | 65 | 55 | Illinois-Chicago (285) | Final | W | 10 |
| 10 | 2017-12-11 | Alabama A&M (351) | 59 | 83 | DePaul (190) | Final | W | 24 |
| 11 | 2017-12-16 | Northwestern (115) | 62 | 60 | DePaul (143) | Final | L | -2 |
| 12 | 2017-12-21 | Miami (OH) (164) | 66 | 83 | DePaul (159) | Final | W | 17 |
| 13 | 2017-12-27 | Villanova (2) | 103 | 85 | DePaul (127) | Final | L | -18 |
| 14 | 2017-12-30 | DePaul (127) | 72 | 77 | Xavier (6) | Final | L | -5 |
| 15 | 2018-01-02 | Georgetown (91) | 90 | 81 | DePaul (137) | Final | L | -9 |
| 16 | 2018-01-06 | DePaul (137) | 91 | 74 | St. John's (59) | Final | W | 17 |
| 17 | 2018-01-12 | Providence (56) | 71 | 64 | DePaul (128) | Final | L | -7 |
| 18 | 2018-01-15 | DePaul (128) | 52 | 70 | Marquette (39) | Final | L | -18 |
| 19 | 2018-01-20 | Butler (32) | 79 | 67 | DePaul (138) | Final | L | -12 |
| 20 | 2018-01-24 | DePaul (146) | 74 | 73 | Georgetown (82) | Final | W | 1 |
| 21 | 2018-01-28 | Seton Hall (28) | 86 | 70 | DePaul (146) | Final | L | -16 |
| 22 | 2018-02-03 | DePaul (137) | 57 | 80 | Butler (32) | Final | L | -23 |
| 23 | 2018-02-07 | Creighton (19) | 76 | 75 | DePaul (137) | Final | L | -1 |
| 24 | 2018-02-10 | DePaul (137) | 80 | 63 | Providence (42) | Final | W | 17 |
| 25 | 2018-02-14 | St. John's (72) | 77 | 76 | DePaul (120) | Final | L | -1 |
| 26 | 2018-02-18 | DePaul (120) | 77 | 82 | Seton Hall (32) | Final | L | -5 |
| 27 | 2018-02-21 | DePaul (125) | 62 | 93 | Villanova (2) | Final | L | -31 |
| 28 | 2018-02-24 | Marquette (46) | 62 | 70 | DePaul (125) | Final | W | 8 |
| 29 | 2018-02-27 | DePaul (116) | 57 | 82 | Creighton (24) | Final | L | -25 |
| 30 | 2018-03-03 | Xavier (5) | 65 | 62 | DePaul (116) | Final | L | -3 |
| 31 | 2018-03-07 | DePaul (123) | 69 | 72 | Marquette (43) | Final | L | -3 |