Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-11-10 | Yale (141) | 76 | 92 | Creighton (26) | Final | W | 16 |
| 2 | 2017-11-12 | Alcorn State (275) | 72 | 109 | Creighton (26) | Final | W | 37 |
| 3 | 2017-11-15 | Creighton (26) | 92 | 88 | Northwestern (32) | Final | W | 4 |
| 4 | 2017-11-20 | UCLA (6) | 89 | 100 | Creighton (26) | Final | W | 11 |
| 5 | 2017-11-21 | Baylor (57) | 65 | 59 | Creighton (40) | Final | L | -6 |
| 6 | 2017-11-25 | SIU-Edwardsville (222) | 66 | 103 | Creighton (40) | Final | W | 37 |
| 7 | 2017-12-01 | Creighton (31) | 74 | 91 | Gonzaga (27) | Final | L | -17 |
| 8 | 2017-12-05 | North Dakota (234) | 68 | 111 | Creighton (59) | Final | W | 43 |
| 9 | 2017-12-09 | Nebraska (96) | 65 | 75 | Creighton (59) | Final | W | 10 |
| 10 | 2017-12-15 | Maryland-Eastern Shore (330) | 36 | 87 | Creighton (36) | Final | W | 51 |
| 11 | 2017-12-18 | Texas-Arlington (99) | 81 | 90 | Creighton (36) | Final | W | 9 |
| 12 | 2017-12-20 | South Carolina Upstate (337) | 62 | 116 | Creighton (30) | Final | W | 54 |
| 13 | 2017-12-28 | Creighton (24) | 84 | 90 | Seton Hall (20) | Final | L | -6 |
| 14 | 2017-12-31 | Providence (71) | 64 | 83 | Creighton (24) | Final | W | 19 |
| 15 | 2018-01-03 | St. John's (59) | 71 | 78 | Creighton (29) | Final | W | 7 |
| 16 | 2018-01-06 | Creighton (29) | 90 | 66 | Georgetown (91) | Final | W | 24 |
| 17 | 2018-01-09 | Butler (29) | 74 | 85 | Creighton (20) | Final | W | 11 |
| 18 | 2018-01-13 | Creighton (20) | 70 | 92 | Xavier (9) | Final | L | -22 |
| 19 | 2018-01-17 | Seton Hall (18) | 63 | 80 | Creighton (22) | Final | W | 17 |
| 20 | 2018-01-20 | Creighton (22) | 71 | 85 | Providence (57) | Final | L | -14 |
| 21 | 2018-01-23 | Creighton (23) | 68 | 63 | St. John's (92) | Final | W | 5 |
| 22 | 2018-01-27 | Georgetown (82) | 77 | 85 | Creighton (23) | Final | W | 8 |
| 23 | 2018-02-01 | Creighton (22) | 78 | 98 | Villanova (2) | Final | L | -20 |
| 24 | 2018-02-07 | Creighton (19) | 76 | 75 | DePaul (137) | Final | W | 1 |
| 25 | 2018-02-10 | Xavier (4) | 72 | 71 | Creighton (19) | Final | L | -1 |
| 26 | 2018-02-13 | Bemidji State | 46 | 94 | Creighton (20) | Final | W | 48 |
| 27 | 2018-02-17 | Marquette (52) | 90 | 86 | Creighton (20) | Final | L | -4 |
| 28 | 2018-02-20 | Creighton (22) | 70 | 93 | Butler (29) | Final | L | -23 |
| 29 | 2018-02-24 | Villanova (2) | 83 | 89 | Creighton (22) | Final/OT | W | 6 |
| 30 | 2018-02-27 | DePaul (116) | 57 | 82 | Creighton (24) | Final | W | 25 |
| 31 | 2018-03-03 | Creighton (24) | 81 | 85 | Marquette (50) | Final | L | -4 |
| 32 | 2018-03-08 | Providence (57) | 72 | 68 | Creighton (25) | Final/OT | L | -4 |
| 33 | 2018-03-16 | Kansas State (82) | 69 | 59 | Creighton (32) | Final - 0:00 | L | -10 |