Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Appalachian State (159) | 81 | 61 | South Carolina State (355) | Final | L | -20 |
| 2 | 2020-11-28 | South Carolina State (355) | 78 | 101 | Bowling Green (168) | Final | L | -23 |
| 3 | 2020-12-02 | South Carolina State (355) | 38 | 75 | Clemson (36) | Final | L | -37 |
| 4 | 2020-12-05 | South Carolina State (355) | 56 | 77 | UNC-Asheville (244) | Final | L | -21 |
| 5 | 2020-12-07 | South Carolina State (355) | 40 | 78 | Charlotte (173) | Final | L | -38 |
| 6 | 2020-12-11 | South Carolina State (355) | 63 | 90 | Charleston (123) | Final | L | -27 |
| 7 | 2020-12-13 | Jacksonville (281) | 60 | 58 | South Carolina State (355) | Final | L | -2 |
| 8 | 2020-12-15 | South Carolina State (355) | 52 | 82 | Liberty (93) | Final | L | -30 |
| 9 | 2020-12-18 | South Carolina State (355) | 56 | 62 | Presbyterian (264) | Final | L | -6 |
| 10 | 2020-12-21 | South Carolina State (355) | 52 | 118 | Furman (157) | Final | L | -66 |
| 11 | 2020-12-23 | South Carolina State (355) | 0 | 0 | South Carolina (110) | Cancelled | - | - |
| 12 | 2020-12-23 | South Carolina State (354) | South Carolina (151) | Cancelled | - | - | ||
| 13 | 2021-01-02 | North Carolina A&T (294) | 97 | 86 | South Carolina State (355) | Final | L | -11 |
| 14 | 2021-01-03 | North Carolina A&T (294) | 73 | 66 | South Carolina State (355) | Final | L | -7 |
| 15 | 2021-01-10 | South Carolina State (355) | 68 | 70 | Florida A&M (297) | Final | L | -2 |
| 16 | 2021-01-11 | South Carolina State (355) | 0 | 0 | Florida A&M (297) | Postponed | - | - |
| 17 | 2021-01-16 | South Carolina State (355) | 0 | 0 | North Carolina Central (341) | Postponed | - | - |
| 18 | 2021-01-17 | South Carolina State (355) | 0 | 0 | North Carolina Central (341) | Postponed | - | - |
| 19 | 2021-01-23 | South Carolina State | 0 | 0 | Florida A&M | Cancelled | - | - |
| 20 | 2021-01-24 | South Carolina State | 0 | 0 | Florida A&M | Cancelled | - | - |
| 21 | 2021-02-01 | South Carolina State (355) | 77 | 91 | North Carolina Central (341) | Final | L | -14 |
| 22 | 2021-02-02 | South Carolina State (355) | 63 | 64 | North Carolina Central (341) | Final | L | -1 |
| 23 | 2021-02-06 | South Carolina State (355) | 0 | 0 | North Carolina A&T (294) | Postponed | - | - |
| 24 | 2021-02-07 | South Carolina State (355) | 0 | 0 | North Carolina A&T (294) | Postponed | - | - |
| 25 | 2021-02-20 | North Carolina Central (341) | 0 | 0 | South Carolina State (355) | Cancelled | - | - |
| 26 | 2021-02-21 | North Carolina Central (341) | 0 | 0 | South Carolina State (355) | Cancelled | - | - |
| 27 | 2021-02-25 | Florida A&M (297) | 75 | 67 | South Carolina State (355) | Final | L | -8 |
| 28 | 2021-02-27 | Florida A&M (297) | 57 | 63 | South Carolina State (355) | Final | W | 6 |
| 29 | 2021-02-28 | Florida A&M (297) | 63 | 58 | South Carolina State (355) | Final | L | -5 |
| 30 | 2021-03-03 | South Carolina State (355) | 0 | 0 | North Carolina A&T (294) | Cancelled | - | - |
| 31 | 2021-03-04 | South Carolina State (355) | 0 | 0 | North Carolina A&T (294) | Cancelled | - | - |