Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-11-11 | Savannah State (298) | 71 | 113 | Iowa State (22) | Final | W | 42 |
| 2 | 2016-11-14 | Mount St Mary's (279) | 55 | 73 | Iowa State (22) | Final | W | 18 |
| 3 | 2016-11-20 | The Citadel (313) | 63 | 130 | Iowa State (22) | Final | W | 67 |
| 4 | 2016-11-24 | Indiana State (169) | 71 | 73 | Iowa State (22) | Final | W | 2 |
| 5 | 2016-11-25 | Iowa State (22) | 73 | 56 | Miami (8) | Final | W | 17 |
| 6 | 2016-11-27 | Iowa State (22) | 71 | 73 | Gonzaga (29) | Final | L | -2 |
| 7 | 2016-12-01 | Cincinnati (32) | 55 | 54 | Iowa State (23) | Final/OT | L | -1 |
| 8 | 2016-12-05 | Nebraska-Omaha (263) | 47 | 91 | Iowa State (23) | Final | W | 44 |
| 9 | 2016-12-08 | Iowa State (33) | 64 | 78 | Iowa (215) | Final | L | -14 |
| 10 | 2016-12-17 | Drake (334) | 80 | 97 | Iowa State (46) | Final | W | 17 |
| 11 | 2016-12-20 | Mississippi Valley State (350) | 60 | 88 | Iowa State (49) | Final | W | 28 |
| 12 | 2016-12-30 | Texas Tech (33) | 56 | 63 | Iowa State (47) | Final | W | 7 |
| 13 | 2017-01-04 | Iowa State (34) | 63 | 65 | Baylor (2) | Final | L | -2 |
| 14 | 2017-01-07 | Texas (113) | 70 | 79 | Iowa State (34) | Final | W | 9 |
| 15 | 2017-01-11 | Iowa State (32) | 96 | 86 | Oklahoma State (56) | Final | W | 10 |
| 16 | 2017-01-14 | Iowa State (32) | 77 | 84 | TCU (37) | Final | L | -7 |
| 17 | 2017-01-16 | Kansas (7) | 76 | 72 | Iowa State (32) | Final | L | -4 |
| 18 | 2017-01-21 | Iowa State (29) | 92 | 87 | Oklahoma (108) | Final/2OT | W | 5 |
| 19 | 2017-01-24 | Kansas State (30) | 65 | 70 | Iowa State (32) | Final | W | 5 |
| 20 | 2017-01-28 | Iowa State (32) | 78 | 84 | Vanderbilt (79) | Final | L | -6 |
| 21 | 2017-01-31 | West Virginia (10) | 85 | 72 | Iowa State (31) | Final | L | -13 |
| 22 | 2017-02-04 | Iowa State (31) | 92 | 89 | Kansas (5) | Final/OT | W | 3 |
| 23 | 2017-02-07 | Iowa State (30) | 65 | 67 | Texas (100) | Final | L | -2 |
| 24 | 2017-02-11 | Oklahoma (107) | 64 | 80 | Iowa State (30) | Final | W | 16 |
| 25 | 2017-02-15 | Iowa State (32) | 87 | 79 | Kansas State (39) | Final | W | 8 |
| 26 | 2017-02-18 | TCU (41) | 71 | 84 | Iowa State (32) | Final | W | 13 |
| 27 | 2017-02-20 | Iowa State (32) | 82 | 80 | Texas Tech (53) | Final/OT | W | 2 |
| 28 | 2017-02-25 | Baylor (12) | 69 | 72 | Iowa State (27) | Final | W | 3 |
| 29 | 2017-02-28 | Oklahoma State (28) | 83 | 86 | Iowa State (26) | Final | W | 3 |
| 30 | 2017-03-03 | Iowa State (26) | 76 | 87 | West Virginia (11) | Final | L | -11 |
| 31 | 2017-03-09 | Oklahoma State (28) | 83 | 92 | Iowa State (25) | Final | W | 9 |
| 32 | 2017-03-10 | TCU (62) | 63 | 84 | Iowa State (25) | Final | W | 21 |
| 33 | 2017-03-11 | Iowa State (7) | 80 | 74 | West Virginia (50) | Final | W | 6 |
| 34 | 2017-03-16 | Nevada (49) | 73 | 84 | Iowa State (25) | Final | W | 11 |
| 35 | 2017-03-18 | Iowa State (25) | 76 | 80 | Purdue (16) | Final | L | -4 |