Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-11-17 | Oklahoma (14) | 84 | 78 | Memphis (84) | Final | W | 6 |
| 2 | 2015-11-20 | McNeese State (288) | 56 | 85 | Oklahoma (14) | Final | W | 29 |
| 3 | 2015-11-24 | Incarnate Word (204) | 63 | 96 | Oklahoma (14) | Final | W | 33 |
| 4 | 2015-11-29 | Wisconsin (3) | 48 | 65 | Oklahoma (14) | Final | W | 17 |
| 5 | 2015-12-03 | Central Arkansas (349) | 68 | 111 | Oklahoma (14) | Final | W | 43 |
| 6 | 2015-12-07 | Oklahoma (14) | 78 | 55 | Villanova (2) | Final | W | 23 |
| 7 | 2015-12-12 | Oral Roberts (69) | 73 | 96 | Oklahoma (14) | Final | W | 23 |
| 8 | 2015-12-19 | Creighton (76) | 74 | 87 | Oklahoma (4) | Final | W | 13 |
| 9 | 2015-12-22 | Oklahoma (3) | 88 | 60 | Washington State (118) | Final | W | 28 |
| 10 | 2015-12-23 | Oklahoma (3) | 84 | 81 | Hawaii (84) | Final | W | 3 |
| 11 | 2015-12-25 | Harvard (243) | 71 | 83 | Oklahoma (3) | Final | W | 12 |
| 12 | 2016-01-02 | Iowa State (13) | 83 | 87 | Oklahoma (3) | Final | W | 4 |
| 13 | 2016-01-04 | Oklahoma (3) | 106 | 109 | Kansas (6) | Final/3OT | L | -3 |
| 14 | 2016-01-09 | Kansas State (46) | 76 | 86 | Oklahoma (1) | Final | W | 10 |
| 15 | 2016-01-13 | Oklahoma (2) | 74 | 72 | Oklahoma State (110) | Final | W | 2 |
| 16 | 2016-01-16 | West Virginia (7) | 68 | 70 | Oklahoma (2) | Final | W | 2 |
| 17 | 2016-01-18 | Oklahoma (2) | 77 | 82 | Iowa State (19) | Final | L | -5 |
| 18 | 2016-01-23 | Oklahoma (1) | 82 | 72 | Baylor (24) | Final | W | 10 |
| 19 | 2016-01-26 | Texas Tech (40) | 67 | 91 | Oklahoma (1) | Final | W | 24 |
| 20 | 2016-01-30 | Oklahoma (1) | 77 | 75 | LSU (76) | Final | W | 2 |
| 21 | 2016-02-02 | TCU (126) | 72 | 95 | Oklahoma (1) | Final | W | 23 |
| 22 | 2016-02-06 | Oklahoma (1) | 69 | 80 | Kansas State (48) | Final | L | -11 |
| 23 | 2016-02-08 | Texas (31) | 60 | 63 | Oklahoma (1) | Final | W | 3 |
| 24 | 2016-02-13 | Kansas (7) | 76 | 72 | Oklahoma (3) | Final | L | -4 |
| 25 | 2016-02-17 | Oklahoma (3) | 63 | 65 | Texas Tech (41) | Final | L | -2 |
| 26 | 2016-02-20 | Oklahoma (3) | 76 | 62 | West Virginia (5) | Final | W | 14 |
| 27 | 2016-02-24 | Oklahoma State (101) | 49 | 71 | Oklahoma (4) | Final | W | 22 |
| 28 | 2016-02-27 | Oklahoma (4) | 63 | 76 | Texas (26) | Final | L | -13 |
| 29 | 2016-03-01 | Baylor (20) | 71 | 73 | Oklahoma (5) | Final | W | 2 |
| 30 | 2016-03-05 | Oklahoma (5) | 75 | 67 | TCU (130) | Final | W | 8 |
| 31 | 2016-03-10 | Iowa State (19) | 76 | 79 | Oklahoma (5) | Final | W | 3 |
| 32 | 2016-03-11 | Oklahoma (5) | 67 | 69 | West Virginia (7) | Final | L | -2 |
| 33 | 2016-03-18 | Cal State-Bakersfield | 68 | 82 | Oklahoma (6) | Final - 0:00 | W | 14 |
| 34 | 2016-03-20 | Virginia Commonwealth (44) | 81 | 85 | Oklahoma (6) | Final - 0:00 | W | 4 |
| 35 | 2016-03-24 | Texas A&M (19) | 63 | 77 | Oklahoma (6) | Final - 0:00 | W | 14 |
| 36 | 2016-03-26 | Oklahoma (6) | 80 | 68 | Oregon (10) | Final - 0:00 | W | 12 |
| 37 | 2016-04-02 | Villanova (2) | 95 | 51 | Oklahoma (6) | Final - 0:00 | L | -44 |