Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-11-10 | Elon (159) | 68 | 97 | Duke (10) | Final | W | 29 |
| 2 | 2017-11-11 | Utah Valley (209) | 69 | 99 | Duke (10) | Final | W | 30 |
| 3 | 2017-11-14 | Duke (10) | 88 | 81 | Michigan State (39) | Final | W | 7 |
| 4 | 2017-11-17 | Southern (317) | 61 | 78 | Duke (10) | Final | W | 17 |
| 5 | 2017-11-20 | Furman (112) | 63 | 92 | Duke (10) | Final | W | 29 |
| 6 | 2017-11-23 | Portland State (67) | 81 | 99 | Duke (13) | Final | W | 18 |
| 7 | 2017-11-24 | Duke (13) | 85 | 78 | Texas (33) | Final/OT | W | 7 |
| 8 | 2017-11-26 | Duke (13) | 87 | 84 | Florida (43) | Final | W | 3 |
| 9 | 2017-11-29 | Duke (2) | 91 | 81 | Indiana (140) | Final | W | 10 |
| 10 | 2017-12-02 | South Dakota (105) | 80 | 96 | Duke (2) | Final | W | 16 |
| 11 | 2017-12-05 | St. Francis (PA) (241) | 67 | 124 | Duke (1) | Final | W | 57 |
| 12 | 2017-12-09 | Duke (1) | 84 | 89 | Boston College (107) | Final | L | -5 |
| 13 | 2017-12-20 | Evansville (104) | 40 | 104 | Duke (6) | Final | W | 64 |
| 14 | 2017-12-30 | Florida State (16) | 93 | 100 | Duke (3) | Final | W | 7 |
| 15 | 2018-01-06 | Duke (1) | 85 | 96 | North Carolina State (67) | Final | L | -11 |
| 16 | 2018-01-10 | Duke (7) | 87 | 52 | Pittsburgh (145) | Final | W | 35 |
| 17 | 2018-01-13 | Wake Forest (105) | 71 | 89 | Duke (7) | Final | W | 18 |
| 18 | 2018-01-15 | Duke (7) | 83 | 75 | Miami (30) | Final | W | 8 |
| 19 | 2018-01-20 | Pittsburgh (170) | 54 | 81 | Duke (6) | Final | W | 27 |
| 20 | 2018-01-23 | Duke (4) | 84 | 70 | Wake Forest (123) | Final | W | 14 |
| 21 | 2018-01-27 | Virginia (2) | 65 | 63 | Duke (4) | Final | L | -2 |
| 22 | 2018-01-29 | Notre Dame (52) | 66 | 88 | Duke (4) | Final | W | 22 |
| 23 | 2018-02-03 | Duke (4) | 77 | 81 | St. John's (101) | Final | L | -4 |
| 24 | 2018-02-08 | Duke (8) | 78 | 82 | North Carolina (17) | Final | L | -4 |
| 25 | 2018-02-11 | Duke (8) | 80 | 69 | Georgia Tech (109) | Final | W | 11 |
| 26 | 2018-02-14 | Virginia Tech (34) | 52 | 74 | Duke (9) | Final | W | 22 |
| 27 | 2018-02-18 | Duke (9) | 66 | 57 | Clemson (11) | Final | W | 9 |
| 28 | 2018-02-21 | Louisville (37) | 56 | 82 | Duke (5) | Final | W | 26 |
| 29 | 2018-02-24 | Syracuse (45) | 44 | 60 | Duke (5) | Final | W | 16 |
| 30 | 2018-02-26 | Duke (5) | 63 | 64 | Virginia Tech (33) | Final | L | -1 |
| 31 | 2018-03-03 | North Carolina (9) | 64 | 74 | Duke (4) | Final | W | 10 |
| 32 | 2018-03-08 | Notre Dame (56) | 70 | 88 | Duke (5) | Final | W | 18 |
| 33 | 2018-03-09 | North Carolina (10) | 74 | 69 | Duke (5) | Final | L | -5 |
| 34 | 2018-03-17 | Rhode Island (153) | 62 | 87 | Duke (13) | Final - 0:00 | W | 25 |
| 35 | 2018-03-23 | Syracuse (93) | 65 | 69 | Duke (13) | Final - 0:00 | W | 4 |
| 36 | 2018-03-25 | Duke (13) | 81 | 85 | Kansas (3) | Final (OT) - 0:00 | L | -4 |