Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-11-10 | Southern (317) | 55 | 102 | Illinois (55) | Final | L | -47 |
| 2 | 2017-11-13 | Southern (317) | 74 | 83 | Marshall (146) | Final | L | -9 |
| 3 | 2017-11-15 | Southern (317) | 58 | 86 | Missouri State (142) | Final | L | -28 |
| 4 | 2017-11-17 | Southern (317) | 61 | 78 | Duke (10) | Final | L | -17 |
| 5 | 2017-11-19 | Southern (317) | 67 | 80 | North Carolina Central (187) | Final | L | -13 |
| 6 | 2017-11-22 | Tennessee-Martin (253) | 66 | 69 | Southern (350) | Final | W | 3 |
| 7 | 2017-11-29 | Wiley | 69 | 92 | Southern (325) | Final | W | 23 |
| 8 | 2017-12-06 | Southern (330) | 76 | 95 | Tulane (81) | Final | L | -19 |
| 9 | 2017-12-09 | Southern (330) | 60 | 76 | Central Florida (73) | Final | L | -16 |
| 10 | 2017-12-10 | Southern (330) | 60 | 91 | Iowa (160) | Final | L | -31 |
| 11 | 2017-12-14 | Florida A&M (338) | 50 | 68 | Southern (333) | Final | W | 18 |
| 12 | 2017-12-20 | Southern (318) | 60 | 80 | Baylor (42) | Final | L | -20 |
| 13 | 2017-12-29 | Ecclesia College | 57 | 98 | Southern (313) | Final | W | 41 |
| 14 | 2018-01-01 | Southern (313) | 66 | 78 | Texas Southern (314) | Final | L | -12 |
| 15 | 2018-01-03 | Southern (299) | 74 | 78 | Prairie View A&M (266) | Final | L | -4 |
| 16 | 2018-01-06 | Grambling (307) | 69 | 80 | Southern (299) | Final | W | 11 |
| 17 | 2018-01-08 | Jackson State (331) | 65 | 61 | Southern (299) | Final | L | -4 |
| 18 | 2018-01-13 | Southern (313) | 76 | 78 | Arkansas-Pine Bluff (347) | Final/OT | L | -2 |
| 19 | 2018-01-15 | Southern (313) | 78 | 70 | Mississippi Valley State (351) | Final/OT | W | 8 |
| 20 | 2018-01-20 | Alabama State (344) | 61 | 63 | Southern (331) | Final | W | 2 |
| 21 | 2018-01-22 | Alabama A&M (347) | 61 | 62 | Southern (331) | Final | W | 1 |
| 22 | 2018-01-27 | Alcorn State (341) | 48 | 61 | Southern (327) | Final | W | 13 |
| 23 | 2018-02-03 | Southern (319) | 68 | 69 | Grambling (305) | Final | L | -1 |
| 24 | 2018-02-05 | Southern (326) | 67 | 62 | Jackson State (327) | Final | W | 5 |
| 25 | 2018-02-10 | Arkansas-Pine Bluff (321) | 62 | 70 | Southern (326) | Final | W | 8 |
| 26 | 2018-02-12 | Mississippi Valley State (351) | 51 | 55 | Southern (326) | Final | W | 4 |
| 27 | 2018-02-17 | Southern (313) | 71 | 67 | Alabama State (343) | Final | W | 4 |
| 28 | 2018-02-19 | Southern (313) | 60 | 50 | Alabama A&M (351) | Final | W | 10 |
| 29 | 2018-02-24 | Southern (313) | 85 | 89 | Alcorn State (338) | Final | L | -4 |
| 30 | 2018-03-01 | Texas Southern (310) | 90 | 88 | Southern (317) | Final | L | -2 |
| 31 | 2018-03-03 | Prairie View A&M (299) | 77 | 69 | Southern (317) | Final | L | -8 |
| 32 | 2018-03-06 | Jackson State (333) | 60 | 62 | Southern (325) | Final | W | 2 |
| 33 | 2018-03-09 | Southern (325) | 65 | 71 | Arkansas-Pine Bluff (328) | Final | L | -6 |