Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2024-11-04 | Lafayette (323) | 63 | 75 | Villanova (29) | Final | W | 12 |
| 2 | 2024-11-06 | Columbia (1) | 90 | 80 | Villanova (176) | Final | L | -10 |
| 3 | 2024-11-08 | NJIT (356) | 54 | 91 | Villanova (118) | Final | W | 37 |
| 4 | 2024-11-12 | Villanova (168) | 76 | 83 | Saint Joseph's (125) | Final | L | -7 |
| 5 | 2024-11-15 | Virginia (75) | 70 | 60 | Villanova (195) | Final | L | -10 |
| 6 | 2024-11-19 | Penn (326) | 49 | 93 | Villanova (172) | Final | W | 44 |
| 7 | 2024-11-24 | Villanova (185) | 75 | 76 | Maryland (27) | Final | L | -1 |
| 8 | 2024-11-27 | Rider (195) | 48 | 72 | Villanova (128) | Final | W | 24 |
| 9 | 2024-12-03 | Cincinnati (68) | 60 | 68 | Villanova (98) | Final | W | 8 |
| 10 | 2024-12-07 | Villanova (89) | 94 | 65 | Temple (177) | Final | W | 29 |
| 11 | 2024-12-11 | Fairleigh Dickinson (334) | 72 | 86 | Villanova (97) | Final | W | 14 |
| 12 | 2024-12-17 | Seton Hall (186) | 67 | 79 | Villanova (86) | Final | W | 12 |
| 13 | 2024-12-21 | Villanova (93) | 79 | 86 | Creighton (68) | Final | L | -7 |
| 14 | 2025-01-01 | Villanova (81) | 73 | 65 | Butler (95) | Final | W | 8 |
| 15 | 2025-01-04 | DePaul (102) | 56 | 100 | Villanova (73) | Final | W | 44 |
| 16 | 2025-01-08 | Connecticut (41) | 66 | 68 | Villanova (69) | Final | W | 2 |
| 17 | 2025-01-11 | Villanova (71) | 68 | 80 | St. John's (28) | Final | L | -12 |
| 18 | 2025-01-14 | Villanova (80) | 63 | 69 | Xavier (67) | Final | L | -6 |
| 19 | 2025-01-17 | Providence (98) | 73 | 75 | Villanova (72) | Final | W | 2 |
| 20 | 2025-01-20 | Georgetown (72) | 64 | 63 | Villanova (78) | Final | L | -1 |
| 21 | 2025-01-24 | Villanova (79) | 74 | 87 | Marquette (12) | Final | L | -13 |
| 22 | 2025-02-01 | Creighton (37) | 62 | 60 | Villanova (80) | Final | L | -2 |
| 23 | 2025-02-05 | Villanova (75) | 59 | 49 | DePaul (142) | Final | W | 10 |
| 24 | 2025-02-09 | Xavier (92) | 68 | 80 | Villanova (29) | Final | W | 12 |
| 25 | 2025-02-12 | St. John's (16) | 71 | 73 | Villanova (62) | Final | W | 2 |
| 26 | 2025-02-15 | Villanova (69) | 62 | 75 | Providence (97) | Final | L | -13 |
| 27 | 2025-02-18 | Villanova (73) | 59 | 66 | Connecticut (42) | Final | L | -7 |
| 28 | 2025-02-21 | Marquette (27) | 66 | 81 | Villanova (68) | Final | W | 15 |
| 29 | 2025-02-26 | Villanova (64) | 59 | 54 | Seton Hall (215) | Final | W | 5 |
| 30 | 2025-03-01 | Butler (80) | 70 | 80 | Villanova (29) | Final | W | 10 |
| 31 | 2025-03-04 | Villanova (67) | 73 | 75 | Georgetown (86) | Final | L | -2 |
| 32 | 2025-03-12 | Seton Hall (228) | 55 | 67 | Villanova (65) | Final | W | 12 |
| 33 | 2025-03-13 | Villanova (65) | 56 | 73 | Connecticut (40) | Final | L | -17 |
| 34 | 2025-04-01 | Colorado (87) | 64 | 85 | Villanova (68) | Final | W | 21 |
| 35 | 2025-04-03 | Villanova (68) | 60 | 59 | USC (67) | Final | W | 1 |
| 36 | 2025-04-05 | Central Florida (74) | 104 | 98 | Villanova (68) | Final (OT) | L | -6 |