NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Richmond (43) | 64 | 85 | Virginia Tech (39) | Final | W | 21 |
| 2 | 2020-11-28 | Liberty (144) | 66 | 81 | Virginia Tech (39) | Final | W | 15 |
| 3 | 2020-12-01 | George Washington (160) | 57 | 92 | Virginia Tech (39) | Final | W | 35 |
| 4 | 2020-12-04 | Appalachian State (226) | 59 | 84 | Virginia Tech (39) | Final | W | 25 |
| 5 | 2020-12-06 | Gardner-Webb (303) | 39 | 73 | Virginia Tech (39) | Final | W | 34 |
| 6 | 2020-12-10 | Pittsburgh (279) | 71 | 88 | Virginia Tech (39) | Final | W | 17 |
| 7 | 2020-12-17 | Virginia Tech (39) | 78 | 84 | Notre Dame (20) | Final | L | -6 |
| 8 | 2020-12-20 | Virginia (322) | 0 | 0 | Virginia Tech (8) | Postponed | - | - |
| 9 | 2020-12-31 | Florida State (129) | 73 | 63 | Virginia Tech (39) | Final | L | -10 |
| 10 | 2021-01-03 | Virginia Tech (38) | Duke (59) | Cancelled | - | - | ||
| 11 | 2021-01-03 | Virginia Tech (39) | 0 | 0 | Duke (8) | Cancelled | - | - |
| 12 | 2021-01-07 | North Carolina State (2) | 0 | 0 | Virginia Tech (50) | Cancelled | - | - |
| 13 | 2021-01-07 | Louisville (13) | 71 | 67 | Virginia Tech (39) | Final | L | -4 |
| 14 | 2021-01-10 | Virginia Tech (39) | 54 | 56 | Georgia Tech (93) | Final | L | -2 |
| 15 | 2021-01-14 | Virginia Tech (59) | 66 | 54 | North Carolina (44) | Final | W | 12 |
| 16 | 2021-01-17 | Wake Forest (154) | 67 | 64 | Virginia Tech (39) | Final | L | -3 |
| 17 | 2021-01-21 | Notre Dame (20) | 65 | 60 | Virginia Tech (39) | Final | L | -5 |
| 18 | 2021-01-24 | Virginia Tech (39) | 87 | 89 | North Carolina State (27) | Final | L | -2 |
| 19 | 2021-01-28 | Louisville (4) | Virginia Tech (52) | Cancelled | - | - | ||
| 20 | 2021-01-28 | North Carolina State (27) | 71 | 83 | Virginia Tech (39) | Final/OT | W | 12 |
| 21 | 2021-01-31 | North Carolina (14) | 69 | 73 | Virginia Tech (39) | Final | W | 4 |
| 22 | 2021-02-02 | Virginia (38) | 0 | 0 | Virginia Tech (39) | Cancelled | - | - |
| 23 | 2021-02-04 | Virginia Tech (39) | 74 | 55 | Pittsburgh (279) | Final | W | 19 |
| 24 | 2021-02-07 | Florida State (59) | Virginia Tech (42) | Cancelled | - | - | ||
| 25 | 2021-02-11 | Virginia Tech (39) | 75 | 55 | Miami (64) | Final | W | 20 |
| 26 | 2021-02-14 | Virginia Tech (39) | 0 | 0 | Boston College (259) | Cancelled | - | - |
| 27 | 2021-02-18 | Duke (8) | 0 | 0 | Virginia Tech (39) | Cancelled | - | - |
| 28 | 2021-02-21 | Syracuse (34) | 68 | 76 | Virginia Tech (39) | Final | W | 8 |
| 29 | 2021-02-25 | Virginia Tech (39) | 70 | 64 | Clemson (47) | Final | W | 6 |
| 30 | 2021-02-28 | Virginia Tech (41) | Virginia (268) | Cancelled | - | - | ||
| 31 | 2021-02-28 | North Carolina (14) | 68 | 63 | Virginia Tech (39) | Final | L | -5 |
| 32 | 2021-03-04 | Miami (62) | 64 | 72 | Virginia Tech (37) | Final | W | 8 |
| 33 | 2021-03-05 | Virginia Tech (39) | 55 | 68 | North Carolina State (27) | Final | L | -13 |
| 34 | 2021-03-21 | Marquette (34) | 63 | 70 | Virginia Tech (36) | Final | W | 7 |
| 35 | 2021-03-23 | Virginia Tech (36) | 48 | 90 | Baylor (2) | Final | L | -42 |