NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | St. Francis (NY) (323) | 0 | 0 | St. John's (87) | Cancelled | - | - |
| 2 | 2020-11-28 | St. John's (87) | 70 | 44 | Fairleigh Dickinson (105) | Final | W | 26 |
| 3 | 2020-12-01 | Saint Peter's (340) | 47 | 85 | St. John's (87) | Final | W | 38 |
| 4 | 2020-12-04 | Georgetown (119) | 0 | 0 | St. John's (87) | Postponed | - | - |
| 5 | 2020-12-06 | Villanova (35) | 74 | 65 | St. John's (87) | Final | L | -9 |
| 6 | 2020-12-10 | St. John's (87) | 88 | 93 | Delaware (241) | Final | L | -5 |
| 7 | 2020-12-13 | St. John's (87) | 61 | 63 | Massachusetts (95) | Final | L | -2 |
| 8 | 2020-12-16 | St. John's (87) | 62 | 66 | Marquette (83) | Final | L | -4 |
| 9 | 2020-12-19 | St. John's (87) | 53 | 76 | Providence (147) | Final | L | -23 |
| 10 | 2020-12-22 | St. Bonaventure (195) | 57 | 60 | St. John's (87) | Final | W | 3 |
| 11 | 2021-01-06 | Xavier (190) | 0 | 0 | St. John's (87) | Postponed | - | - |
| 12 | 2021-01-09 | Butler (157) | 56 | 64 | St. John's (87) | Final | W | 8 |
| 13 | 2021-01-13 | St. John's (173) | 84 | 101 | DePaul (29) | Final | L | -17 |
| 14 | 2021-01-17 | Marquette (83) | 72 | 61 | St. John's (87) | Final | L | -11 |
| 15 | 2021-01-20 | St. John's (87) | 64 | 87 | Seton Hall (70) | Final | L | -23 |
| 16 | 2021-01-23 | Creighton (98) | 0 | 0 | St. John's (87) | Cancelled | - | - |
| 17 | 2021-01-25 | St. John's (180) | 78 | 81 | Villanova (41) | Final/OT | L | -3 |
| 18 | 2021-01-27 | St. John's (87) | 70 | 53 | Georgetown (119) | Final | W | 17 |
| 19 | 2021-01-30 | Providence (147) | 0 | 0 | St. John's (87) | Cancelled | - | - |
| 20 | 2021-02-03 | St. John's (87) | 62 | 94 | Connecticut (2) | Final | L | -32 |
| 21 | 2021-02-06 | St. John's (87) | 0 | 0 | Xavier (190) | Cancelled | - | - |
| 22 | 2021-02-10 | DePaul (31) | 81 | 73 | St. John's (187) | Final | L | -8 |
| 23 | 2021-02-13 | St. John's (87) | 47 | 35 | Butler (157) | Final | W | 12 |
| 24 | 2021-02-17 | Connecticut (2) | 77 | 32 | St. John's (87) | Final | L | -45 |
| 25 | 2021-02-21 | Providence (147) | 47 | 65 | St. John's (87) | Final | W | 18 |
| 26 | 2021-02-24 | Georgetown (119) | 62 | 58 | St. John's (87) | Final/OT | L | -4 |
| 27 | 2021-02-27 | St. John's (87) | 0 | 0 | Creighton (98) | Cancelled | - | - |
| 28 | 2021-03-01 | Seton Hall (80) | 59 | 43 | St. John's (169) | Final | L | -16 |
| 29 | 2021-03-05 | Xavier (190) | 57 | 65 | St. John's (87) | Final | W | 8 |
| 30 | 2021-03-06 | St. John's (87) | 41 | 77 | Connecticut (2) | Final | L | -36 |