NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-09 | Paul Quinn | 70 | 83 | Prairie View A&M (334) | Final | W | 13 |
| 2 | 2021-11-11 | Prairie View A&M (361) | 47 | 102 | Nebraska (36) | Final | L | -55 |
| 3 | 2021-11-16 | Prairie View A&M (270) | 71 | 88 | New Mexico (72) | Final | L | -17 |
| 4 | 2021-11-20 | Portland State (111) | 75 | 61 | Prairie View A&M (270) | Final | L | -14 |
| 5 | 2021-11-21 | Prairie View A&M (270) | 54 | 80 | Portland (14) | Final | L | -26 |
| 6 | 2021-11-23 | Prairie View A&M (361) | 71 | 86 | Wichita State (266) | Final | L | -15 |
| 7 | 2021-12-01 | Huston-Tillotson | 40 | 83 | Prairie View A&M (325) | Final | W | 43 |
| 8 | 2021-12-03 | Southeastern Louisiana (276) | 79 | 54 | Prairie View A&M (325) | Final | L | -25 |
| 9 | 2021-12-13 | Jarvis Christian | 0 | 0 | Prairie View A&M (333) | Postponed | - | - |
| 10 | 2021-12-15 | Prairie View A&M (329) | 46 | 66 | Lamar (201) | Final | L | -20 |
| 11 | 2021-12-19 | Prairie View A&M (361) | 39 | 108 | Iowa State (37) | Final | L | -69 |
| 12 | 2021-12-30 | Jarvis Christian | 52 | 80 | Prairie View A&M (334) | Final | W | 28 |
| 13 | 2022-01-03 | Prairie View A&M (334) | 65 | 57 | Grambling (303) | Final | W | 8 |
| 14 | 2022-01-05 | Prairie View A&M (361) | 52 | 89 | Southern (213) | Final | L | -37 |
| 15 | 2022-01-08 | Mississippi Valley State (342) | 77 | 84 | Prairie View A&M (361) | Final | W | 7 |
| 16 | 2022-01-10 | Arkansas-Pine Bluff (306) | 73 | 63 | Prairie View A&M (361) | Final | L | -10 |
| 17 | 2022-01-15 | Prairie View A&M (331) | 52 | 87 | Jackson State (155) | Final | L | -35 |
| 18 | 2022-01-17 | Prairie View A&M (331) | 63 | 55 | Alcorn State (343) | Final | W | 8 |
| 19 | 2022-01-22 | Alabama State (256) | 58 | 61 | Prairie View A&M (328) | Final | W | 3 |
| 20 | 2022-01-24 | Alabama A&M (299) | 70 | 64 | Prairie View A&M (328) | Final | L | -6 |
| 21 | 2022-01-29 | Texas Southern (306) | 91 | 77 | Prairie View A&M (322) | Final | L | -14 |
| 22 | 2022-02-05 | Prairie View A&M (361) | 70 | 60 | Bethune-Cookman (352) | Final | W | 10 |
| 23 | 2022-02-07 | Prairie View A&M (361) | 64 | 51 | Florida A&M (338) | Final | W | 13 |
| 24 | 2022-02-12 | Southern (251) | 55 | 62 | Prairie View A&M (321) | Final | W | 7 |
| 25 | 2022-02-14 | Grambling (291) | 63 | 71 | Prairie View A&M (321) | Final | W | 8 |
| 26 | 2022-02-19 | Prairie View A&M (307) | 61 | 66 | Arkansas-Pine Bluff (281) | Final | L | -5 |
| 27 | 2022-02-21 | Prairie View A&M (307) | 70 | 60 | Mississippi Valley State (348) | Final | W | 10 |
| 28 | 2022-02-26 | Alcorn State (353) | 61 | 52 | Prairie View A&M (310) | Final | L | -9 |
| 29 | 2022-02-28 | Jackson State (111) | 91 | 76 | Prairie View A&M (310) | Final | L | -15 |
| 30 | 2022-03-05 | Prairie View A&M (317) | 61 | 56 | Texas Southern (279) | Final | W | 5 |
| 31 | 2022-03-10 | Prairie View A&M (312) | 58 | 60 | Alabama State (278) | Final | L | -2 |