NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | Cal Poly (350) | 40 | 108 | Stanford (56) | Final | L | -68 |
| 2 | 2020-12-02 | Nevada (255) | Cal Poly (331) | Cancelled | - | - | ||
| 3 | 2020-12-10 | New Mexico State (298) | 60 | 70 | Cal Poly (350) | Final | W | 10 |
| 4 | 2020-12-14 | Santa Clara (86) | 56 | 57 | Cal Poly (350) | Final | W | 1 |
| 5 | 2020-12-15 | Santa Clara (86) | 59 | 70 | Cal Poly (350) | Final | W | 11 |
| 6 | 2020-12-19 | Cal Poly (350) | 51 | 61 | California Baptist (130) | Final | L | -10 |
| 7 | 2020-12-21 | Cal Poly (350) | 73 | 63 | San Diego State (63) | Final | W | 10 |
| 8 | 2020-12-27 | Hawaii (172) | 0 | 0 | Cal Poly (83) | Cancelled | - | - |
| 9 | 2020-12-28 | Hawaii (172) | 0 | 0 | Cal Poly (83) | Cancelled | - | - |
| 10 | 2021-01-01 | Cal Poly (350) | 90 | 68 | UC-San Diego (107) | Final | W | 22 |
| 11 | 2021-01-02 | Cal Poly (350) | 63 | 74 | UC-San Diego (107) | Final | L | -11 |
| 12 | 2021-01-08 | Cal State-Bakersfield (326) | 0 | 0 | Cal Poly (350) | Cancelled | - | - |
| 13 | 2021-01-09 | Cal State-Bakersfield (326) | 0 | 0 | Cal Poly (350) | Cancelled | - | - |
| 14 | 2021-01-15 | Cal Poly (350) | 0 | 0 | UC-Riverside (267) | Cancelled | - | - |
| 15 | 2021-01-16 | Cal Poly (350) | 0 | 0 | UC-Riverside (267) | Cancelled | - | - |
| 16 | 2021-01-22 | UC-Irvine (101) | 63 | 52 | Cal Poly (350) | Final | L | -11 |
| 17 | 2021-01-23 | UC-Irvine (101) | 79 | 70 | Cal Poly (350) | Final/OT | L | -9 |
| 18 | 2021-01-29 | Cal Poly (167) | Cal State-Northridge | Cancelled | - | - | ||
| 19 | 2021-01-29 | Cal Poly (350) | 56 | 43 | UC-Riverside (267) | Final | W | 13 |
| 20 | 2021-01-30 | Cal Poly (167) | Cal State-Northridge | Cancelled | - | - | ||
| 21 | 2021-01-30 | Cal Poly (350) | 67 | 53 | UC-Riverside (267) | Final | W | 14 |
| 22 | 2021-02-05 | Hawaii (134) | 71 | 79 | Cal Poly (350) | Final/OT | W | 8 |
| 23 | 2021-02-06 | Hawaii (134) | 66 | 60 | Cal Poly (350) | Final | L | -6 |
| 24 | 2021-02-12 | Cal Poly (350) | 70 | 65 | Cal State-Fullerton (200) | Final/OT | W | 5 |
| 25 | 2021-02-13 | Cal Poly (350) | 49 | 65 | Cal State-Fullerton (200) | Final | L | -16 |
| 26 | 2021-02-19 | Long Beach State (335) | 44 | 55 | Cal Poly (350) | Final | W | 11 |
| 27 | 2021-02-20 | Long Beach State (335) | 42 | 45 | Cal Poly (350) | Final | W | 3 |
| 28 | 2021-02-26 | Cal Poly (350) | 47 | 63 | UC-Davis (153) | Final | L | -16 |
| 29 | 2021-02-27 | Cal Poly (350) | 53 | 62 | UC-Davis (153) | Final | L | -9 |
| 30 | 2021-03-05 | UC-Santa Barbara (161) | 46 | 76 | Cal Poly (350) | Final | W | 30 |
| 31 | 2021-03-06 | UC-Santa Barbara (161) | 78 | 68 | Cal Poly (350) | Final | L | -10 |
| 32 | 2021-03-10 | Cal Poly (169) | 61 | 60 | Long Beach State (164) | Final | W | 1 |
| 33 | 2021-03-12 | Cal Poly (169) | 59 | 68 | UC-Irvine (182) | Final | L | -9 |