NCAA Women's Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-12-21 | California Baptist (130) | 0 | 0 | UC-San Diego (107) | Cancelled | - | - |
| 2 | 2021-01-01 | Cal Poly (350) | 90 | 68 | UC-San Diego (107) | Final | L | -22 |
| 3 | 2021-01-02 | Cal Poly (350) | 63 | 74 | UC-San Diego (107) | Final | W | 11 |
| 4 | 2021-01-08 | UC-San Diego (107) | 0 | 0 | Cal State-Northridge (293) | Cancelled | - | - |
| 5 | 2021-01-09 | UC-San Diego (107) | 0 | 0 | Cal State-Northridge (293) | Cancelled | - | - |
| 6 | 2021-01-15 | UC-Santa Barbara (161) | 0 | 0 | UC-San Diego (107) | Cancelled | - | - |
| 7 | 2021-01-16 | UC-Santa Barbara (161) | 71 | 73 | UC-San Diego (107) | Final | W | 2 |
| 8 | 2021-01-22 | UC-San Diego (107) | 62 | 80 | UC-Davis (153) | Final | L | -18 |
| 9 | 2021-01-23 | UC-San Diego (107) | 46 | 58 | UC-Davis (153) | Final | L | -12 |
| 10 | 2021-01-29 | Long Beach State (335) | 54 | 50 | UC-San Diego (107) | Final | L | -4 |
| 11 | 2021-01-30 | Long Beach State (335) | 74 | 53 | UC-San Diego (107) | Final | L | -21 |
| 12 | 2021-02-05 | UC-San Diego (217) | Hawaii (283) | Cancelled | - | - | ||
| 13 | 2021-02-06 | UC-San Diego (217) | Hawaii (283) | Cancelled | - | - | ||
| 14 | 2021-02-12 | Cal State-Bakersfield (326) | 62 | 38 | UC-San Diego (107) | Final | L | -24 |
| 15 | 2021-02-13 | Cal State-Bakersfield (326) | 69 | 66 | UC-San Diego (107) | Final | L | -3 |
| 16 | 2021-02-19 | UC-San Diego (107) | 63 | 59 | UC-Riverside (267) | Final | W | 4 |
| 17 | 2021-02-20 | UC-San Diego (107) | 74 | 67 | UC-Riverside (267) | Final | W | 7 |
| 18 | 2021-02-26 | UC-Irvine (101) | 63 | 66 | UC-San Diego (107) | Final | W | 3 |
| 19 | 2021-02-27 | UC-Irvine (101) | 64 | 58 | UC-San Diego (107) | Final | L | -6 |
| 20 | 2021-03-05 | UC-San Diego (107) | 57 | 60 | Cal State-Fullerton (200) | Final | L | -3 |
| 21 | 2021-03-06 | UC-San Diego (107) | 68 | 66 | Cal State-Fullerton (200) | Final/OT | W | 2 |