Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-09-12 | Clemson (3) | 37 | Wake Forest (47) | 13 | Final | L | -24 |
| 2 | 2020-09-19 | Wake Forest (47) | 42 | North Carolina State (109) | 45 | Final | L | -3 |
| 3 | 2020-09-26 | Notre Dame (9) | 0 | Wake Forest (47) | 0 | Cancelled | - | - |
| 4 | 2020-10-02 | Campbell (251) | 14 | Wake Forest (124) | 66 | Final | W | 52 |
| 5 | 2020-10-09 | Campbell (252) | 0 | Wake Forest (109) | 0 | Cancelled | - | - |
| 6 | 2020-10-17 | Virginia (98) | 23 | Wake Forest (102) | 40 | Final | W | 17 |
| 7 | 2020-10-24 | Virginia Tech (14) | 16 | Wake Forest (31) | 23 | Final | W | 7 |
| 8 | 2020-10-31 | Wake Forest (31) | 38 | Syracuse (118) | 14 | Final | W | 24 |
| 9 | 2020-11-14 | Wake Forest (28) | 53 | North Carolina (26) | 59 | Final | L | -6 |
| 10 | 2020-11-21 | Wake Forest (40) | 0 | Duke (90) | 0 | Cancelled | - | - |
| 11 | 2020-11-28 | Miami (9) | 0 | Wake Forest (43) | 0 | Cancelled | - | - |
| 12 | 2020-11-28 | Wake Forest (43) | 0 | Louisville (81) | 0 | Cancelled | - | - |
| 13 | 2020-12-05 | Wake Forest (39) | 0 | Louisville (83) | 0 | Cancelled | - | - |
| 14 | 2020-12-05 | Miami (9) | 0 | Wake Forest (39) | 0 | Cancelled | - | - |
| 15 | 2020-12-12 | Notre Dame (3) | 0 | Wake Forest (36) | 0 | Cancelled | - | - |
| 16 | 2020-12-12 | Wake Forest (36) | 21 | Louisville (84) | 45 | Final | L | -24 |
| 17 | 2020-12-19 | Wake Forest (36) | 0 | Louisville (84) | 0 | Cancelled | - | - |
| 18 | 2020-12-19 | Florida State (110) | 0 | Wake Forest (36) | 0 | Cancelled | - | - |
| 19 | 2020-12-30 | Wake Forest (56) | 28 | Wisconsin (54) | 42 | Final | L | -14 |