Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-09-12 | North Carolina State (109) | 0 | Virginia Tech (50) | 0 | Cancelled | - | - |
| 2 | 2020-09-19 | Virginia (33) | 0 | Virginia Tech (50) | 0 | Cancelled | - | - |
| 3 | 2020-09-26 | North Carolina State (109) | 24 | Virginia Tech (50) | 45 | Final | W | 21 |
| 4 | 2020-10-03 | Virginia Tech (15) | 38 | Duke (126) | 31 | Final | W | 7 |
| 5 | 2020-10-10 | Virginia Tech (9) | 45 | North Carolina (8) | 56 | Final | L | -11 |
| 6 | 2020-10-17 | Boston College (16) | 14 | Virginia Tech (15) | 40 | Final | W | 26 |
| 7 | 2020-10-24 | Virginia Tech (14) | 16 | Wake Forest (31) | 23 | Final | L | -7 |
| 8 | 2020-10-31 | Virginia Tech (29) | 42 | Louisville (97) | 35 | Final | W | 7 |
| 9 | 2020-11-07 | Liberty (28) | 38 | Virginia Tech (23) | 35 | Final | L | -3 |
| 10 | 2020-11-14 | Miami (8) | 25 | Virginia Tech (36) | 24 | Final | L | -1 |
| 11 | 2020-11-21 | Virginia Tech (42) | 14 | Pittsburgh (68) | 47 | Final | L | -33 |
| 12 | 2020-12-05 | Clemson (5) | 45 | Virginia Tech (55) | 10 | Final | L | -35 |
| 13 | 2020-12-12 | Virginia (39) | 15 | Virginia Tech (59) | 33 | Final | W | 18 |