Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-09-03 | Western Kentucky (75) | 14 | Vanderbilt (100) | 12 | Final | L | -2 |
| 2 | 2015-09-12 | Georgia (11) | 31 | Vanderbilt (100) | 14 | Final | L | -17 |
| 3 | 2015-09-19 | Austin Peay | 7 | Vanderbilt | 47 | Final | W | 40 |
| 4 | 2015-09-26 | Vanderbilt (89) | 16 | Ole Miss (2) | 27 | Final | L | -11 |
| 5 | 2015-10-03 | Vanderbilt | 17 | Middle Tennessee | 13 | Final | W | 4 |
| 6 | 2015-10-17 | Vanderbilt (72) | 10 | South Carolina (80) | 19 | Final | L | -9 |
| 7 | 2015-10-24 | Missouri (57) | 3 | Vanderbilt (84) | 10 | Final | W | 7 |
| 8 | 2015-10-31 | Vanderbilt (77) | 0 | Houston (20) | 34 | Final | L | -34 |
| 9 | 2015-11-07 | Vanderbilt (81) | 7 | Florida (8) | 9 | Final | L | -2 |
| 10 | 2015-11-14 | Kentucky (64) | 17 | Vanderbilt (77) | 21 | Final | W | 4 |
| 11 | 2015-11-21 | Texas A&M (28) | 25 | Vanderbilt (68) | 0 | Final | L | -25 |
| 12 | 2015-11-28 | Vanderbilt (74) | 28 | Tennessee (29) | 53 | Final | L | -25 |