Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2015-09-05 | Southeast Missouri State | 3 | Missouri | 34 | Final | W | 31 |
| 2 | 2015-09-12 | Missouri (16) | 27 | Arkansas State (85) | 20 | Final | W | 7 |
| 3 | 2015-09-19 | Connecticut | 6 | Missouri | 9 | Final | W | 3 |
| 4 | 2015-09-26 | Missouri (33) | 13 | Kentucky (44) | 21 | Final | L | -8 |
| 5 | 2015-10-03 | South Carolina (62) | 10 | Missouri (57) | 24 | Final | W | 14 |
| 6 | 2015-10-10 | Florida (1) | 21 | Missouri (44) | 3 | Final | L | -18 |
| 7 | 2015-10-17 | Missouri (49) | 6 | Georgia (45) | 9 | Final | L | -3 |
| 8 | 2015-10-24 | Missouri (57) | 3 | Vanderbilt (84) | 10 | Final | L | -7 |
| 9 | 2015-11-05 | Mississippi State | 31 | Missouri | 13 | Final | L | -18 |
| 10 | 2015-11-14 | BYU (28) | 16 | Missouri (71) | 20 | Final | W | 4 |
| 11 | 2015-11-21 | Tennessee (29) | 19 | Missouri (60) | 8 | Final | L | -11 |
| 12 | 2015-11-27 | Missouri (62) | 3 | Arkansas (36) | 28 | Final | L | -25 |