Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | Howard (243) | 28 | Hampton (212) | 31 | Final | W | 3 |
| 2 | 2022-09-10 | Tuskegee | 10 | Hampton (212) | 42 | Final | W | 32 |
| 3 | 2022-09-17 | Hampton (162) | 17 | Norfolk State (237) | 7 | Final | W | 10 |
| 4 | 2022-09-24 | Hampton (174) | 3 | Delaware (96) | 35 | Final | L | -32 |
| 5 | 2022-10-08 | Maine (218) | 31 | Hampton (204) | 24 | Final | L | -7 |
| 6 | 2022-10-15 | Hampton (196) | 38 | Albany (227) | 37 | Final(OT) | W | 1 |
| 7 | 2022-10-22 | Richmond (143) | 41 | Hampton (203) | 10 | Final | L | -31 |
| 8 | 2022-10-29 | Hampton (207) | 10 | Villanova (180) | 24 | Final | L | -14 |
| 9 | 2022-11-05 | William & Mary (102) | 20 | Hampton (209) | 14 | Final | L | -6 |
| 10 | 2022-11-12 | Elon (129) | 38 | Hampton (204) | 24 | Final | L | -14 |
| 11 | 2022-11-19 | Hampton (212) | 7 | Towson (174) | 27 | Final | L | -20 |