Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2019-08-31 | Idaho (203) | 7 | Penn State (15) | 79 | Final | W | 72 |
| 2 | 2019-09-07 | Buffalo (53) | 13 | Penn State (15) | 45 | Final | W | 32 |
| 3 | 2019-09-14 | Pittsburgh (45) | 10 | Penn State (15) | 17 | Final | W | 7 |
| 4 | 2019-09-27 | Penn State (10) | 59 | Maryland (38) | 0 | Final | W | 59 |
| 5 | 2019-10-05 | Purdue (96) | 7 | Penn State (5) | 35 | Final | W | 28 |
| 6 | 2019-10-12 | Penn State (5) | 17 | Iowa (22) | 12 | Final | W | 5 |
| 7 | 2019-10-19 | Michigan (17) | 21 | Penn State (5) | 28 | Final | W | 7 |
| 8 | 2019-10-26 | Penn State (3) | 28 | Michigan State (29) | 7 | Final | W | 21 |
| 9 | 2019-11-09 | Penn State (3) | 26 | Minnesota (9) | 31 | Final | L | -5 |
| 10 | 2019-11-16 | Indiana (31) | 27 | Penn State (4) | 34 | Final | W | 7 |
| 11 | 2019-11-23 | Penn State (4) | 17 | Ohio State (1) | 28 | Final | L | -11 |
| 12 | 2019-11-30 | Rutgers (122) | 6 | Penn State (6) | 27 | Final | W | 21 |
| 13 | 2019-12-28 | Memphis (8) | 39 | Penn State (7) | 53 | Final | W | 14 |