Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2019-08-29 | Robert Morris (253) | 10 | Buffalo (53) | 38 | Final | W | 28 |
| 2 | 2019-09-07 | Buffalo (53) | 13 | Penn State (15) | 45 | Final | L | -32 |
| 3 | 2019-09-14 | Buffalo (53) | 17 | Liberty (105) | 35 | Final | L | -18 |
| 4 | 2019-09-21 | Temple (57) | 22 | Buffalo (53) | 38 | Final | W | 16 |
| 5 | 2019-09-28 | Buffalo (82) | 20 | Miami (OH) (106) | 34 | Final | L | -14 |
| 6 | 2019-10-05 | Ohio (112) | 21 | Buffalo (87) | 20 | Final(OT) | L | -1 |
| 7 | 2019-10-19 | Buffalo (109) | 21 | Akron (169) | 0 | Final | W | 21 |
| 8 | 2019-10-26 | Central Michigan (88) | 20 | Buffalo (102) | 43 | Final | W | 23 |
| 9 | 2019-11-02 | Buffalo (89) | 43 | Eastern Michigan (93) | 14 | Final | W | 29 |
| 10 | 2019-11-14 | Buffalo (79) | 27 | Kent State (115) | 30 | Final | L | -3 |
| 11 | 2019-11-20 | Toledo (81) | 30 | Buffalo (84) | 49 | Final | W | 19 |
| 12 | 2019-11-29 | Bowling Green (129) | 7 | Buffalo (76) | 49 | Final | W | 42 |
| 13 | 2019-12-20 | Buffalo (69) | 31 | Charlotte (84) | 9 | Final | W | 22 |