Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-09-01 | Tennessee-Martin | 14 | Missouri | 51 | Final | W | 37 |
| 2 | 2018-09-08 | Wyoming (80) | 13 | Missouri (53) | 40 | Final | W | 27 |
| 3 | 2018-09-15 | Missouri (53) | 40 | Purdue (45) | 37 | Final | W | 3 |
| 4 | 2018-09-22 | Georgia (3) | 43 | Missouri (53) | 29 | Final | L | -14 |
| 5 | 2018-10-06 | Missouri (39) | 35 | South Carolina (31) | 37 | Final | L | -2 |
| 6 | 2018-10-13 | Missouri (50) | 10 | Alabama (1) | 39 | Final | L | -29 |
| 7 | 2018-10-20 | Memphis (74) | 33 | Missouri (60) | 65 | Final | W | 32 |
| 8 | 2018-10-27 | Kentucky (9) | 15 | Missouri (43) | 14 | Final | L | -1 |
| 9 | 2018-11-03 | Missouri (44) | 38 | Florida (9) | 17 | Final | W | 21 |
| 10 | 2018-11-10 | Vanderbilt (55) | 28 | Missouri (26) | 33 | Final | W | 5 |
| 11 | 2018-11-17 | Missouri (21) | 50 | Tennessee (44) | 17 | Final | W | 33 |
| 12 | 2018-11-23 | Arkansas (115) | 0 | Missouri (15) | 38 | Final | W | 38 |
| 13 | 2018-12-31 | Missouri (15) | 33 | Oklahoma State (54) | 38 | Final | L | -5 |