Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2017-08-31 | Kentucky Wesleyan | 7 | Murray State | 67 | Final | W | 60 |
| 2 | 2017-09-16 | Murray State (203) | 21 | Missouri State (191) | 28 | Final | L | -7 |
| 3 | 2017-09-23 | Austin Peay (249) | 27 | Murray State (203) | 7 | Final | L | -20 |
| 4 | 2017-09-30 | Murray State (224) | 10 | Louisville (43) | 55 | Final | L | -45 |
| 5 | 2017-10-07 | Murray State | 13 | Tennessee-Martin | 10 | Final | W | 3 |
| 6 | 2017-10-14 | Eastern Illinois | 27 | Murray State | 24 | Final/2OT | L | -3 |
| 7 | 2017-10-28 | Eastern Kentucky | 26 | Murray State | 13 | Final | L | -13 |
| 8 | 2017-11-04 | Murray State | 23 | Jacksonville State | 59 | Final | L | -36 |
| 9 | 2017-11-11 | Tennessee Tech | 21 | Murray State | 31 | Final | W | 10 |
| 10 | 2017-11-18 | Murray State | 10 | Southeast Missouri State | 21 | Final | L | -11 |