Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-02 | Holy Cross (139) | 31 | Merrimack (229) | 17 | Final | L | -14 |
| 2 | 2022-09-09 | Assumption | 17 | Merrimack (229) | 45 | Final | W | 28 |
| 3 | 2022-09-16 | Merrimack (177) | 13 | Harvard (220) | 7 | Final | W | 6 |
| 4 | 2022-09-24 | Merrimack (160) | 26 | Delaware State (218) | 13 | Final | W | 13 |
| 5 | 2022-10-01 | Long Island (251) | 23 | Merrimack (158) | 24 | Final | W | 1 |
| 6 | 2022-10-08 | Merrimack (153) | 28 | Duquesne (230) | 21 | Final | W | 7 |
| 7 | 2022-10-15 | Wagner (251) | 17 | Merrimack (151) | 54 | Final | W | 37 |
| 8 | 2022-10-22 | Sacred Heart (205) | 25 | Merrimack (148) | 31 | Final | W | 6 |
| 9 | 2022-10-29 | Merrimack (144) | 17 | Stonehill (213) | 10 | Final | W | 7 |
| 10 | 2022-11-12 | Merrimack (152) | 20 | Central Connecticut State (252) | 14 | Final | W | 6 |