Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-01 | The Citadel | 24 | Mercer | 23 | Final | L | -1 |
| 2 | 2016-09-10 | Mercer | 10 | Georgia Tech | 35 | Final | L | -25 |
| 3 | 2016-09-17 | Tennessee Tech | 27 | Mercer | 34 | Final | W | 7 |
| 4 | 2016-10-01 | Mercer | 33 | Virginia Military | 30 | Final/OT | W | 3 |
| 5 | 2016-10-08 | Mercer | 31 | Chattanooga | 52 | Final | L | -21 |
| 6 | 2016-10-15 | Western Carolina | 24 | Mercer | 38 | Final | W | 14 |
| 7 | 2016-10-22 | Mercer | 41 | Austin Peay | 34 | Final | W | 7 |
| 8 | 2016-10-29 | Mercer (166) | 21 | Wofford (161) | 31 | Final | L | -10 |
| 9 | 2016-11-05 | East Tennessee State | 13 | Mercer | 21 | Final | W | 8 |
| 10 | 2016-11-12 | Mercer (170) | 19 | Samford (133) | 24 | Final | L | -5 |
| 11 | 2016-11-19 | Furman (180) | 24 | Mercer (172) | 27 | Final | W | 3 |