Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2016-09-02 | Colorado State (83) | 7 | Colorado (92) | 44 | Final | W | 37 |
| 2 | 2016-09-10 | Idaho State | 7 | Colorado | 56 | Final | W | 49 |
| 3 | 2016-09-17 | Colorado (92) | 28 | Michigan (6) | 45 | Final | L | -17 |
| 4 | 2016-09-24 | Colorado (37) | 41 | Oregon (67) | 38 | Final | W | 3 |
| 5 | 2016-10-01 | Oregon State (89) | 6 | Colorado (28) | 47 | Final | W | 41 |
| 6 | 2016-10-08 | Colorado (22) | 17 | USC (50) | 21 | Final | L | -4 |
| 7 | 2016-10-15 | Arizona State (20) | 16 | Colorado (29) | 40 | Final | W | 24 |
| 8 | 2016-10-22 | Colorado (19) | 10 | Stanford (32) | 5 | Final | W | 5 |
| 9 | 2016-11-03 | UCLA (66) | 10 | Colorado (15) | 20 | Final | W | 10 |
| 10 | 2016-11-12 | Colorado (12) | 49 | Arizona (110) | 24 | Final | W | 25 |
| 11 | 2016-11-19 | Washington State | 24 | Colorado | 38 | Final | W | 14 |
| 12 | 2016-11-26 | Utah (39) | 22 | Colorado (10) | 27 | Final | W | 5 |
| 13 | 2016-12-02 | Colorado (9) | 10 | Washington (5) | 41 | Final | L | -31 |
| 14 | 2016-12-29 | Oklahoma State (28) | 38 | Colorado (10) | 8 | Final | L | -30 |