Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-09-03 | Colgate (222) | 10 | Stanford (109) | 41 | Final | L | -31 |
| 2 | 2022-09-10 | Colgate (222) | 21 | Maine (160) | 18 | Final | W | 3 |
| 3 | 2022-09-17 | Colgate (198) | 14 | Penn (164) | 25 | Final | L | -11 |
| 4 | 2022-09-24 | Holy Cross (93) | 35 | Colgate (195) | 10 | Final | L | -25 |
| 5 | 2022-10-01 | Cornell (185) | 34 | Colgate (215) | 31 | Final | L | -3 |
| 6 | 2022-10-15 | Colgate (205) | 17 | Army (120) | 42 | Final | L | -25 |
| 7 | 2022-10-22 | Georgetown (250) | 24 | Colgate (199) | 34 | Final | W | 10 |
| 8 | 2022-10-29 | Colgate (197) | 13 | Bucknell (244) | 7 | Final | W | 6 |
| 9 | 2022-11-05 | Lafayette (194) | 21 | Colgate (205) | 16 | Final | L | -5 |
| 10 | 2022-11-12 | Colgate (218) | 33 | Lehigh (236) | 36 | Final | L | -3 |
| 11 | 2022-11-19 | Colgate (217) | 38 | Fordham (139) | 52 | Final | L | -14 |