Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | St. Francis (PA) (159) | 80 | 70 | Pittsburgh (99) | Final | W | 10 |
| 2 | 2020-11-28 | UMBC (245) | 80 | 65 | St. Francis (PA) (159) | Final | L | -15 |
| 3 | 2020-12-01 | St. Francis (PA) (234) | 51 | 76 | Virginia (253) | Final | L | -25 |
| 4 | 2020-12-03 | St. Francis (PA) (234) | 62 | 78 | Liberty (126) | Final | L | -16 |
| 5 | 2020-12-05 | Robert Morris (208) | St. Francis (PA) (234) | Cancelled | - | - | ||
| 6 | 2020-12-08 | St. Francis (PA) (276) | 57 | 75 | Mount St Mary's (256) | Final | L | -18 |
| 7 | 2020-12-12 | St. Francis (PA) (276) | Delaware State (327) | Cancelled | - | - | ||
| 8 | 2020-12-12 | St. Francis (PA) (276) | 0 | 0 | St. Bonaventure (202) | Cancelled | - | - |
| 9 | 2021-01-07 | St. Francis (PA) (268) | 75 | 78 | Long Island (221) | Final | L | -3 |
| 10 | 2021-01-08 | St. Francis (PA) (268) | 58 | 71 | Long Island (221) | Final | L | -13 |
| 11 | 2021-01-14 | Bryant (75) | 82 | 89 | St. Francis (PA) (283) | Final | W | 7 |
| 12 | 2021-01-15 | Bryant (75) | 72 | 63 | St. Francis (PA) (283) | Final | L | -9 |
| 13 | 2021-01-21 | St. Francis (PA) (234) | 76 | 58 | Sacred Heart (223) | Final | W | 18 |
| 14 | 2021-01-22 | St. Francis (PA) (234) | 70 | 82 | Sacred Heart (223) | Final | L | -12 |
| 15 | 2021-01-26 | Fairleigh Dickinson (318) | 94 | 92 | St. Francis (PA) (224) | Final (OT) | L | -2 |
| 16 | 2021-01-27 | Fairleigh Dickinson (318) | 82 | 90 | St. Francis (PA) (224) | Final | W | 8 |
| 17 | 2021-01-30 | Central Connecticut State (288) | 59 | 62 | St. Francis (PA) (224) | Final | W | 3 |
| 18 | 2021-01-31 | Central Connecticut State (281) | 85 | 77 | St. Francis (PA) (251) | Final | L | -8 |
| 19 | 2021-02-04 | St. Francis (PA) (251) | 62 | 68 | Merrimack (207) | Final | L | -6 |
| 20 | 2021-02-05 | St. Francis (PA) (251) | 54 | 59 | Merrimack (207) | Final | L | -5 |
| 21 | 2021-02-11 | St. Francis (NY) (241) | 70 | 67 | St. Francis (PA) (263) | Final | L | -3 |
| 22 | 2021-02-12 | St. Francis (NY) (241) | 66 | 80 | St. Francis (PA) (263) | Final | W | 14 |
| 23 | 2021-02-21 | St. Francis (PA) (272) | 68 | 70 | Wagner (143) | Final | L | -2 |
| 24 | 2021-02-25 | Mount St Mary's (189) | 72 | 65 | St. Francis (PA) (272) | Final (OT) | L | -7 |