Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-01-02 | American (249) | 0 | 0 | Loyola-Maryland (325) | Postponed | - | - |
| 2 | 2021-01-03 | Loyola-Maryland (325) | 0 | 0 | American (249) | Cancelled | - | - |
| 3 | 2021-01-09 | Navy (91) | 0 | 0 | Loyola-Maryland (178) | Cancelled | - | - |
| 4 | 2021-01-10 | Loyola-Maryland (178) | 0 | 0 | Navy (91) | Cancelled | - | - |
| 5 | 2021-01-16 | Loyola-Maryland (325) | 75 | 77 | Lafayette (323) | Final | L | -2 |
| 6 | 2021-01-17 | Lafayette (323) | 72 | 70 | Loyola-Maryland (325) | Final | L | -2 |
| 7 | 2021-01-23 | Loyola-Maryland (325) | 70 | 71 | American (249) | Final | L | -1 |
| 8 | 2021-01-24 | American (249) | 81 | 79 | Loyola-Maryland (325) | Final/3OT | L | -2 |
| 9 | 2021-01-30 | Loyola-Maryland (325) | 52 | 70 | Navy (149) | Final | L | -18 |
| 10 | 2021-01-31 | Navy (149) | 0 | 0 | Loyola-Maryland (325) | Postponed | - | - |
| 11 | 2021-02-02 | Navy (67) | 0 | 0 | Loyola-Maryland (303) | Cancelled | - | - |
| 12 | 2021-02-02 | Loyola-Maryland (325) | 0 | 0 | Navy (149) | Postponed | - | - |
| 13 | 2021-02-06 | Bucknell (336) | 0 | 0 | Loyola-Maryland (325) | Postponed | - | - |
| 14 | 2021-02-07 | Lafayette (323) | 62 | 75 | Loyola-Maryland (325) | Final | W | 13 |
| 15 | 2021-02-08 | Loyola-Maryland (325) | 0 | 0 | Bucknell (336) | Cancelled | - | - |
| 16 | 2021-02-08 | Loyola-Maryland (325) | 76 | 80 | Lafayette (323) | Final | L | -4 |
| 17 | 2021-02-13 | Loyola-Maryland (257) | 0 | 0 | Lehigh (270) | Cancelled | - | - |
| 18 | 2021-02-13 | Loyola-Maryland (325) | 94 | 97 | Lafayette (323) | Final/3OT | L | -3 |
| 19 | 2021-02-14 | Lehigh (268) | 0 | 0 | Loyola-Maryland (244) | Cancelled | - | - |
| 20 | 2021-02-14 | Lafayette (323) | 69 | 88 | Loyola-Maryland (325) | Final | W | 19 |
| 21 | 2021-02-17 | American (165) | 0 | 0 | Loyola-Maryland (244) | Cancelled | - | - |
| 22 | 2021-02-20 | Loyola-Maryland (325) | 75 | 47 | Lehigh (276) | Final | W | 28 |
| 23 | 2021-02-21 | Lehigh (276) | 76 | 72 | Loyola-Maryland (325) | Final | L | -4 |
| 24 | 2021-02-24 | Loyola-Maryland | 0 | 0 | American | Cancelled | - | - |
| 25 | 2021-02-24 | American (249) | 49 | 60 | Loyola-Maryland (325) | Final | W | 11 |
| 26 | 2021-02-27 | Navy (149) | 73 | 67 | Loyola-Maryland (325) | Final | L | -6 |
| 27 | 2021-02-28 | Loyola-Maryland (325) | 58 | 66 | Navy (149) | Final | L | -8 |
| 28 | 2021-03-03 | Loyola-Maryland (325) | 0 | 0 | Holy Cross (334) | Cancelled | - | - |
| 29 | 2021-03-06 | Loyola-Maryland (325) | 76 | 68 | Navy (149) | Final | W | 8 |
| 30 | 2021-03-10 | Loyola-Maryland (203) | 67 | 63 | Army (97) | Final | W | 4 |
| 31 | 2021-03-14 | Loyola-Maryland (325) | 72 | 85 | Colgate (239) | Final | L | -13 |