Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-01-04 | Boston University (267) | 83 | 76 | Holy Cross (334) | Final | W | 7 |
| 2 | 2021-01-05 | Holy Cross (334) | 68 | 66 | Boston University (267) | Final | L | -2 |
| 3 | 2021-01-09 | Colgate (239) | 86 | 79 | Boston University (267) | Final | L | -7 |
| 4 | 2021-01-10 | Colgate (239) | 89 | 45 | Boston University (267) | Final | L | -44 |
| 5 | 2021-01-16 | Army (339) | 79 | 59 | Boston University (267) | Final | L | -20 |
| 6 | 2021-01-17 | Army (339) | 76 | 65 | Boston University (267) | Final | L | -11 |
| 7 | 2021-01-23 | Boston University (267) | 81 | 76 | Lafayette (323) | Final | W | 5 |
| 8 | 2021-01-24 | Boston University (267) | 64 | 61 | Lafayette (323) | Final | W | 3 |
| 9 | 2021-01-30 | Boston University (191) | 0 | 0 | Holy Cross (241) | Cancelled | - | - |
| 10 | 2021-01-31 | Holy Cross (334) | 0 | 0 | Boston University (267) | Postponed | - | - |
| 11 | 2021-02-06 | Boston University (267) | 0 | 0 | Colgate (239) | Postponed | - | - |
| 12 | 2021-02-07 | Boston University (267) | 0 | 0 | Colgate (239) | Postponed | - | - |
| 13 | 2021-02-13 | Boston University | 0 | 0 | Army | Cancelled | - | - |
| 14 | 2021-02-13 | Boston University (267) | 65 | 82 | Holy Cross (334) | Final | L | -17 |
| 15 | 2021-02-14 | Boston University | 0 | 0 | Army | Cancelled | - | - |
| 16 | 2021-02-14 | Holy Cross (334) | 68 | 86 | Boston University (267) | Final | W | 18 |
| 17 | 2021-02-17 | Boston University (267) | 78 | 69 | Holy Cross (334) | Final | W | 9 |
| 18 | 2021-02-20 | Boston University (267) | 72 | 82 | Colgate (239) | Final | L | -10 |
| 19 | 2021-02-21 | Boston University (267) | 63 | 78 | Colgate (239) | Final | L | -15 |
| 20 | 2021-02-24 | Holy Cross (334) | 86 | 75 | Boston University (267) | Final | L | -11 |
| 21 | 2021-02-27 | Boston University (267) | 75 | 63 | Army (339) | Final | W | 12 |
| 22 | 2021-02-28 | Boston University (267) | 55 | 57 | Army (339) | Final | L | -2 |
| 23 | 2021-03-03 | Lehigh (276) | 58 | 69 | Boston University (267) | Final | W | 11 |
| 24 | 2021-03-06 | Boston University (267) | 69 | 77 | Colgate (239) | Final | L | -8 |